Molecular complexes macromolecular compounds

Summary Recent achievements in two catalytic reactions, i.e., silylative coupling and cross-metathesis of alkenes and dienes with vinyl-silicon compounds, which resulted in new synthetic routes to organosilicon molecular and macromolecular compounds are presented. The silylative coupling, also called dehydrogenative or trans-silylation and silyl group transfer, is catalyzed by metal complexes which either contain or initiate the formation of M-H and M-Si bonds, where M = Ru, Rh, Co and Ir. Cross-metathesis, which was developed very recently, proceeds in the presence of metallacarbenes, mainly those of rathenium (e.g., Grabbs catalyst). 

TTFs, also named 2,2 -bi-l,3-dithiole, 2,2 -bi-(l,3-dithiolylidene), are one of the most studied systems in the field of molecular materials because of their ability to participate in electrically conducting and superconducting cation radical salts or CT complexes. The utility of TTF derivatives as building blocks in macromolecular and super-molecular structures, molecular-based ferromagnetic compounds, donor moieties in intramolecular D-A systems in... 

A concept that is critical in the complex evaluation of bound residues is the adduct residue. The concept of adduct residue can be applied to any metabolite covalently linked to an endogenous component. Hydrolysis of Ure macromolecular bound residue, whether by enzymatic or chemical means, may lead to lower-molecular-weight adduct residues, free residues, and residue fragments. Since bound residues are derived from reactive metabolites, the reversibility of adduct formation to yield reactive compounds may be a key factor in the safety assessment of bound residues. 

To date, the capability of macromolecular peptides as molecular recognition sites has been poorly characterized. Due to the analytical techniques available, first investigations on host-guest complexes were done in the homogeneous phase [55]. One of the most popular cyclic compounds is the depsipeptide, valinomycin, which can complex potassium ions selectively and carry them through lipid membranes [56], Another interesting receptor is the peptide antibiotic, vancomycin [57], This consists of a complicated tricyclic pep-tidic structure and can be used as chiral selector [58] in capillary electrophoresis and HPLC. 

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