Modular search system

Since all of our common questions are compound oriented we designed a modular search system as shown in Figure 3. 

N. F. Landers and L. M. Petrie, CSAS4 An Enhanced Criticality Safety Analysis Module with an Optimum Pitch Search, Sect. C4 of SCALE A Modular Code System for Performing Standardized Computer Analyses for Licensing Evaluation, NUREG/CR-0200, Rev. 4 (ORNL/NUREG/CSD-2/R4), Vols. I, II, and III (draft Febmary 1990). Available from Radiation Shielding Information Center as CCC-545. 

Figure 3. Flow diagram of modular ACCIS search system...

The examples discussed in this paper demonstrate that Pd-catalyzed coupling reactions can be successfully utilized in the convergent (modular) synthesis of vitamin D-active compounds. The new synthetic routes open an efficient and highly selective access to a variety of vitamin D analogs. While reliable methods exist today for the construction of the triene system and for the synthesis of the ring A precursors, the search for efficient total synthetic approaches to the CD building blocks still remain a challenging task for the future. 

An integrated, modular system for molecular visualization, computation, and 3D database creation and searching for compounds in all areas of chemistry. The base system (ChemCore, ChemModel, ChemGuide, and ChemMovie) provides for molecular building and displays, geometry and energy calcula-... 

The standard software of the CSD system must also develop, not only to keep pace with the ever-increasing reservoir of data to be searched, but also to incorporate new search requirements demanded by the user community and to take advantage of the dramatic improvements in global communications networks. The CSD software must become more modular and extend to an increasing number of (cheaper) computer platforms. Undeniably, it must also become more intuitive and easier to use. 

---