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VII. A Push-Pull Model for Nematode Sperm Amoeboid Motility... [Pg.395]

Fig. 6. Proposed push-pull model for nematode sperm locomotion. Assembly and bundling of MSP filaments into fiber complexes (dark band spanning the lamellipo-dium) pushes the membrane at the leading edge forward. At the same time a second force, associated with disassembly of the fiber complexes at the base of the lamellipo-dium, pulls the cell body forward. In this model, attachments where the cytoskeleton is linked to the membrane and the membrane anchored to the substratum establish traction and separate mechanically the forces produced at opposite ends of the fiber complexes. Thus, rather than canceling each other, these forces can be exerted independently against the substratum. Reproduced from The Journal of Cell Biology, 2000, vol. 149, pp. 7-12 by copyright permission of the Rockefeller University Press. Fig. 6. Proposed push-pull model for nematode sperm locomotion. Assembly and bundling of MSP filaments into fiber complexes (dark band spanning the lamellipo-dium) pushes the membrane at the leading edge forward. At the same time a second force, associated with disassembly of the fiber complexes at the base of the lamellipo-dium, pulls the cell body forward. In this model, attachments where the cytoskeleton is linked to the membrane and the membrane anchored to the substratum establish traction and separate mechanically the forces produced at opposite ends of the fiber complexes. Thus, rather than canceling each other, these forces can be exerted independently against the substratum. Reproduced from The Journal of Cell Biology, 2000, vol. 149, pp. 7-12 by copyright permission of the Rockefeller University Press.
The principles of the push-pull model probably apply generally to amoeboid cell motility. Indeed, a consensus is developing that in both sperm and actin-based crawling cells the force for protrusion is derived from localized cytoskeletal assembly (reviewed by Pollard and Borisy, 2003). However, as applied to nematode sperm locomotion, the model envisions that lamellipod extension and cell body retraction are linked reciprocally to the polymerization state of the cytoskeleton. The lack of structural polarity of MSP filaments, the precise localization of cytoskeletal polymerization and depolymerization at opposite ends of the fiber complexes, and insights gained from reconstitution of cytoskeletal dynamics and motility in vitro and in vivo all support the conclusion that nematode sperm move without using motor proteins and that, instead, they rely on... [Pg.396]

K. J. Duff, H. L. Gray, R. J. Gray, and C. C. Bahler, Chiral stationary phases in concert with homologous chiral mobile phases additives Push/pull model. Chirality 5 (1993), 201... [Pg.1050]

Many other tools for estimating fate and transport, natural attenuation, exposure, and risk estimation, have been integrated into the Applied Risk Assessment Modeling System (ARAMS). As with the aforementioned models, ARAMS models are available as freeware on the Web site http //el.erdc.usace.army.mil/arams/. The ARAMS system is extensive, and builds on various models and databases that are contained within the system, and also pulls information from databases in real time from the Internet. These data are handled within the ARAMS system to provide reports. User-guided interfaces provide the means for operation however, some models may require additional specific expertise. Models such as SEEM and FISHRAND can work independently or within the ARAMS system. [Pg.295]

The house model pulls it together in a simple, manageable format, rooted in a transversal way of thinking wherein some strategic activities and measurements are set universally and some strategic and tactical activities are decentralized, either geographically or sectorally thus its variation encompasses a matrixlike complexity in which countries and business units have different needs—often shaped by the contextual factors. [Pg.385]

Driven by e-commerce s capabilities to empower clients, many companies are moving from the traditional push business model, where manufacturers, suppliers, distributors, and marketers have most of the power, to a customer-driven pull model (E-Future, 2006). This new business model is less product-centric and more directly focused on the individual consumer. To succeed in the business environment, companies have recognized that there is an ongoing shift in the balance of power in the commerce model, from suppliers to customers. [Pg.196]

Pull-based ATP Models Pull-based ATP models perform dynamic resource allocation in direct response to actual customer orders. Models of this type can range from a simple database lookup to sophisticated optimization. The purpose of pull-based ATP models is to make best use of available resources (including raw materials, work-in-process, finished goods, and even production and distribution capacities) to commit customer order requests over a period of time across a supply chain. The time horizon in pull-based ATP models is usually so short that a company can assume full knowledge about the availability of production resources. Pull-based ATP models are responsible for matching complicated customer requests with diversified resource availability. The specific decisions usually involve which orders to accept and, for each order, what quantity and which due date to promise. [Pg.460]

Pull model with latent enminno method variance factor... [Pg.96]

The model has been divided into three steps heat transfer model, pressure model and pulling force model. [Pg.135]

Quantum chemical calculations and a simple push-md-pull model have been used in [195] to explain the allosteric effect in anion binding by the capsule 770. For this purpose, the doublecage framework has been divided into three subsystems as shown in Scheme 4.187, and the DFT-calculated geometrical and thermodynamic parameters are reported in [195] to be in an excellent agreement with the experimental data. [Pg.392]

Dieterich JM, Clever GH, Mata RA (2012) A push-and-pull model for allosteric anion binding in cage complexes. Phys Chem Chem Phys 14(37) 12746-12749... [Pg.418]

The model presented in this chapter ignored the sphemlite structure of the crystalline phase which exists in all semi-crystalline polymers unless being deliberately destroyed by manufacturing process (such as pulling of fibres). The amorphous phases inside a sphemlite and between the spheruhtes are different in many ways. It is possible to account for this difference by modifying the model (Gleadall et al., 2012). However this introduces more parameters into the model. The model assuming... [Pg.68]

It is possible to model pull-out behaviour by predicting two types of pull-out... [Pg.52]

In this chapter, additional observations are therefore used in order to distinguish between different possible flow models. The presence of CO2 introduces a reduction in compressional wave velocity, which in timn results in an increase of travel-time for reflections below the CO2. This pull-down can be observed and quantified from the time-lap>se seismic. A forward modeling of acoustic properties is performed from the flow model, and the modeled pull-down is compared to the observed pull-down. This evaluation will reduce both the uncertainties associated with the flow model and the uncertainties in the rock-physical transforms. Prom the matched flow model and rock-physical... [Pg.410]

Combined Beam-Solid-Gap Model This model introduces a change in the way the contact between the gear teeth occurs. In this model, the contact is modeled through the use of "gap elements," which allow sliding and separation to occur between the two surfaces, but prevent both penetration or overlap of the teeth and tension (as if the surfaces were glued and pulled apart). While this condition enhances the representation of the contact forces, it introduces significant difficulties in the model due to the fact that the... [Pg.293]

Theoretical models and mathematical derivations are developed in enough detail to be comprehensible to the student reader. Only rarely do 1 pull results out of a hat, and 1 scrupulously avoid saying it is obvious that... ... [Pg.727]


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See also in sourсe #XX -- [ Pg.233 ]




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