Mixed venous oxygen saturation

Central venous (superior vena cava) or mixed venous oxygen saturation >70%... 

A recent study would support a mixed venous oxygen saturation of 65% as similar to a central venous oxygen saturation of 70% ... 

Central venous or mixed venous oxygen saturation greater than or equal to 70%... 

Immediate initial resuscitation of a patient in severe sepsis or sepsis-induced tissue B hypoperfusion should be instituted to achieve central venous pressure 8-12 mm Hg mean arterial pressure >65 mm Hg urine output >0.5 mt/kj hour, central venous or mixed venous oxygen saturation >70%... 

Invasive continuous hepatic function monitoring by the fluorescence procedure was also evaluated in rabbits [148]. In this study, a commercial catheter equipped with fiber optic technology for mixed venous oxygen saturation measurements (SVO2) was modified to emit light at 780 nm and detect fluorescence at 840 nm. The catheter was placed into the right jugular vein and advanced... 

O2 transport values and hemodynamics and may increase adverse cardiac effects. Infusion rates should be guided by clinical end points and mixed venous oxygen saturation/central venous oxygen saturation. Decreases in partial pressure of O2, as well as myocardial adverse effects such as tachycardia, ischemic changes on ECG, tachydysrhythmias, and hypotension, are seen. 

A 72-year-old woman, who underwent emergency resection of a giant left atrial myxoma, had pulmonary hypertension (pulmonary artery pressure 40 mmHg) and a low cardiac output (2.21/minute). Inhaled nitric oxide, 40 ppm, before cardiopulmonary bjrpass resulted in pulmonary vasodilatation and a fall in pulmonary artery pressure from 39 to 31 mmHg. This was accompanied by a fall in cardiac output from 2.4 to 1.5 1/minute and a fall in mixed venous oxygen saturation. After bypass, inhaled nitric oxide improved pulmonary and systemic hemodynamics and resulted in a rise in cardiac output from 3.0 to 3.5 l/minute. 

Edwards JD, Mayall RM. Importance of the sampling site for measurement of mixed venous oxygen saturation in shock. Crit Care Med 1998 26 1356-1360. 

Burchell SA, Yu M, Takiguchi SA, Ohta RM. Evaluation of a continuous cardiac output and mixed venous oxygen saturation catheter in critically ill surgery patients. Crit Care Med 1997 2 388-391. 

B. Other useful laboratory studies include electrolytes, glucose, serum lactate, arterial blood gas, mixed venous oxygen saturation, and carboxyhemo-globin (if patient had a smoke inhalation exposure). 

Cyanides. Cyanide levels will be elevated but rapid testing is not widely available. Suspect cyanide poisoning If the patient has severe metabolic acidosis, especially If mixed venous oxygen saturation is greater than 90%. 

B. Other laboratory tests include CBC, electrolytes, glucose, BUN, creatinine, arterial blood gases, amylase/llpase and liver transaminases, chest x-ray, and ECG monitoring. In addition, obtain serum lactate and mixed venous oxygen saturation if cyanide poisoning is suspected (see p 177). 

As further evidence of the modified polymer s excellent hemocompat-ibility, in vivo trials incorporating the polymer into a hemoperfusion device were conducted at the University of Cafifomia at Davis. A polycarbonate cartridge containing lOOmL of the polymer was steam autoclaved at 120°C for 45 min and flushed with 1L of sterile safine prior to use. Several times two healthy canines underwent 5 h of hemoperfusion at a flow rate of 200 mL/min. No adverse effects such as fever or hypotension were noted. Temperature, blood pressure, mixed venous oxygen saturation, and hematocrit were continuously monitored during the procedure and all remained unchanged throughout the procedure. 

Noninvasive or invasive blood pressure Temperature Nerve stimulators Mixed venous oxygen saturation Transesophageal echo cardiography (TEE)... 

Jubran A, Mathru M, Dries D, et al. Continuous recordings of mixed venous oxygen saturation during weaning from mechanical ventilation and the ramifications thereof. Am J Respir Crit Care Med 1998 158(6) 1763-1769. 

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