Mineral metabolism function tests

Calcium— An essential macro mineral necessary for bone formation and other metabolic functions. Controlled experiment— Also called a controlled trial. The dividing into groups of experimental subjects to see what the effects of a drug will be when tested along with a dummy drug or placebo (a drug other than the one being tested). Dermatitis—An inflammation of the skin. A symptom of vitamin deficiency. 

Other laboratory parameters to measure include growth and plasma or serum concentrations of glucose, uric acid, triglycerides, cholesterol, lactate, and liver function tests. Poor bone mineralization has been found in those with GSD-1 therefore, monitoring of serum or plasma markers of bone metabolism including total 25-hydroxyvitamin D and routine DXA scans is suggested [20] (Box 27.6). 

Often, tests such as those described are used in conjunction with tests of other metabolic functions, because the metabolic activities of certain minerals are not always correlated with the levels of the elements which are present in body fluids and tissues. For example, hair may be analyzed for its chromium content in order to determine whether a diabeticlike response to a glucose tolerance test is due to a... 

The tests that are routinely performed provide information concerning hepatocellular and biliary integrity and function, renal function, carbohydrate, protein and lipid metabolism, and mineral and electrolyte balance. Modern analytical techniques require only small sample volumes to make accurate determinations, allowing in-life evaluations of effects in rats and larger species at multiple times during the course of a study without compromising animal health. 

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