Microparticles nanoparticles

Keywords. Controlled drug release, Hydrogels, Microparticles, Nanoparticles, Niosomes, Tablets, Transdermal... 

Microparticles, nanoparticles W/O/W solvent evaporation Model protein, tetanus toxoid PLA-PEG In rats Size-dependent mucosal uptake 66... 

Figure 1 Formulation of controlled drug delivery systems using the supercritical fluid-derived RESS process (A) films, (B) microparticles/nanoparticles/ liposomes, (C) coated products including microcapsules, and (D) microporous foams.

Nanoparticles and/or capsules are colloidal drug delivery systems whose size ranges from 1 to 1000 nm. Similar to microparticles, nanoparticles also offer... 

For the purpose of transdermal delivery, chitosan has been largely processed into hydrogel, membrane, microparticle, nanoparticle, and nanocapsule. In addition, it is also used in the processing of liposome and polymersome. 

Medical Brachytherapy, drug delivery, orthopedics, tissue engineering, imaging Microparticles ++++ Nanoparticles Chips -H-... 

Various DDSs based on PLGA have been developed in recent times. The developed DDS includes microparticles, nanoparticles, injectables, dry powder for inhalation,... 

Keywords Peptides, proteins, biopolymers, microparticles, nanoparticles, drug delivery... 

Keywords Ophthalmology Polymers Inserts Hydrogels Microparticles Nanoparticles Drug delivery... 

A large variety of drug delivery systems are described in the literature, such as liposomes (Torchilin, 2006), micro and nanoparticles (Kumar, 2000), polymeric micelles (Torchilin, 2006), nanocrystals (Muller et al., 2011), among others. Microparticles are usually classified as microcapsules or microspheres (Figure 8). Microspheres are matrix spherical microparticles where the drug may be located on the surface or dissolved into the matrix. Microcapsules are characterized as spherical particles more than Ipm containing a core substance (aqueous or lipid), normally lipid, and are used to deliver poor soluble molecules... 

Xylan-based micro- and nanoparticles have been produced by simple coacervation (Garcia et al., 2001). In the study, sodium hydroxide and chloride acid or acetic acid were used as solvent and non-solvent, respectively. Also, xylan and surfactant concentrations and the molar ratio between sodium hydroxide and chloride acid were observed as parameters for the formation of micro- and nanoparticles by the simple coacervation technique (Garcia et al., 2001). Different xylan concentrations allowed the formation of micro- and nanoparticles. More precisely, microparticles were found for higher concentrations of xylan while nanopartides were produced for lower concentrations of the polymer solution. When the molar ratio between sodium hydroxide and chloride acid was greater than 1 1, the partides settled more rapidly at pH=7.0. Regarding the surfactant variations, an optimal concentration was found however, at higher ones a supernatant layer was observed after 30 days (Garda et al., 2001). 

It is clearly visible from Figure 28.24 that initial moduli of nanocomposites are higher than those of microcomposites at any loading, given that the surface activity and surface area between nanoparticles and microparticles are different. 

Nanoparticles show great promise as devices for the controlled release of drugs, provided that the choice of material for nanoparticle formation is made with the appropriate considerations of the drug cargo, administration route, and the desired site of action. The use of nano- and microparticles as controlled drug-delivery devices has recently been extensively reviewed [97]. 

Wendorf J, Chesko J, Kazzaz J et al (2008) A comparison of anionic nanoparticles and microparticles as vaccine delivery systems. Hum Vaccin 4 44-49... 

The original polymeric latex particles still are widely used for separation and detection. Polymers provide a matrix that can be swollen for embedding other molecules in their core, such as organic dyes or fluorescent molecules. Even nanoparticle quantum dots can be incorporated into larger latex particles to form highly fluorescent composite microparticles. 

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