Micro-total-analysis

Micro Total Analysis Systems (pTAS) are chip-based micro-channel systems that serve for complete analytics. The word Total refers to the monolithic system character of the devices, integrating a multitude of miniature functional elements with minimal dead volumes. The main fields of application are related to biology, pharmacology, and analytical chemistry. Detailed applications of pTAS systems are given in Section 1.9.8. Recently, pTAS developments have strongly influenced the performance of organic syntheses by micro flow (see, e.g., [29]). By this, an overlap with the micro-reactor world was made, which probably will increase more and more. 

J. M., VAN DEN Berg, A. (Eds.), Micro Total Analysis Systems, pp. 661-663, Kluwer Academic Publishers, Dordrecht (2001). 

N., WiDMER, H. M., p-TAS miniaturized total chemical analysis systems, in Proceedings of the Micro Total Analysis System Workshop, pp. 5-27 (Nov. 1994), Enschede, The Netherlands. 

R., Chow, A., Chien, R.-L, Chow, C., Parce, J. W., Commercialized and emerging Lab-on-a-Chip applications, in Ramsey, J. M., van den Berg, A. (Eds.), Micro Total Analysis Systems, pp. 7-9, Kluwer Academic Publishers, Dordrecht (2001). 

D. R., Manz, a.. Micro total analysis systems 2. Analytical standard operations and applications. Anal. Chem. 74,12 (2002) 2637-2652. 

Lindner, D., The pChem Lab project micro total analysis system R D at Sandia National Laboratories, Lab Chip 1 (2001) 15N-19N. 

Micro Total Analysis Systems, pp. 517-518, Kluwer Academic Publishers, Dordrecht (2001). 

Cowen, S. and Craston, D. H., An on-chip miniature liquid chromatography system design, construction and characterization, in Micro Total Analysis Systems, van den Berg and Bergveld, Eds., Kluwer Academic, The Netherlands, 1995, 295. 

Taylor M.T., Belgrader P., Joshi R., Kintz G.A., Northrup M.A., Fully automated sample preparation for pathogen detection performed in a microfluidic cassette. In Micro Total Analysis Systems 2000, Berg, A. van den, Olthuis, W., Bergveld, P., eds. Kluwer Academic Publishers, The Netherlands, pp 670-672, 2000. 

Dittrich PS, Tachikawa K, Manz A (2006) Micro total analysis systems. Latest advancements and trends. Anal Chem 78 3887-3907 Ehrfeld W (1997) (ed) Microreaction technology. Springer, Berlin New York Heidelberg... 

The need for improved sensor performance has led to the emergence of micro and nanofluidics. These fields seek to develop miniaturized analysis systems that combine the desired attributes in a compact and cost-effective setting. These platforms are commonly labeled as labs-on-chip or micro total analysis systems (pTAS)2, often using optical methods to realize a desired functionality. The preeminent role that optics play has recently led to the notion of optofluidics as an independent field that deals with devices and methods in which optics and fluidics enable each other3. Most of the initial lab-on-chip advances, however, occurred in the area of fluidics, while the optical components continued to consist largely of bulk components such as polarizers, filters, lenses, and objectives. 

Reyes D. R. Iossifidis, D. Auroux, P. Manz, A., Micro total analysis systems. 1. Introduction, theory, and technology, Anal. Chem. 2002, 74, 2623 2636... 

Microsyringe injection, gas chromatography, 4 611 Microtex polyester fibers, 13 393 Microthermal analysis, recent developments in, 79 577 Micro total analysis system (pTAS),... 

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