Micro-biosensor

Acetylcholineesterase and choline oxidase A glassy carbon electrode (GCE) modified by electrodepositing sub pm Pt-black particles on the surface. ACh and Ch. micro biosensor arrays were fabricated based on immobilization of AChE—ChO or ChO by cross linking with gentar-aldehyde on Pt-black GCE. Significant enhancement in the performance of these biosensors was achieved. The chronoamperometric response of 1 p biosensor array was linear from 29 to 1200 pM with detection limit of 8.7 pM acetylcholine. [109]... 

Inlet Thermistor Geld tubing Outlet Fig. 7. Schematic illustration of the thermal micro-biosensor fabricated onto a silicon chip... 

E. Tamiya, and I. Karube, Micro-biosensors for chnical and foods analyses. 

N. N. Mishra, S. Retterer, T. J. Zieziulewicz, M. Isaacson, D. Szarowski, D. E. Mousseau, D. A. Lawrence and J. N. Tumer,On-chip micro-biosensor for the detection of human CD4(+) cells based on AC impedance and optical analysis. Biosens Bioelectron., 21, 696-704. (2005). 

Satoh I, Akahane M and Matsumoto K 1991 Analytical applications of immobilized acid urease for urea in flow streams Sensors Actuators B 5 241 Danielsson B 1995 Handbook of Analytical Sciences (London Academic) at press Xie B, Hedberg (Harbom) U, Mecklenburg M and Danielsson B 1993 Fast determination of whole blood glucose with a calorimetric micro-biosensor Sensors Actuators B 15-16 141-4... 

Xie B, Danielsson B, Norberg P, Winquist F and LundstrOm I 1992 Development of a thermal micro-biosensor fabricated on a silicon chip Sensors Actuators B 6 127-30... 

Deng PG, Lee YK, Cheng P (2006) Two-dimensional microbubble actuator array to enhance the efficiency of molecular beacon DNA micro-biosensors. Biosens Bioelectron 21 1443-1450... 

Hiratsuka A, Kojima KI, Muguruma H, Lee KH, Suzuki H, Karube I. (2005) Electron transfer mediator micro-biosensor fabrication by organic plasma process. Biosensors... 

In the literature there are numerous papers on different micro-biosensors used to measure, for instance, glucose or lactate concentration in the body. Some of these sensors use Ag AgCl electrodes with AgCl formed on a silver surface. Potential of such electrodes may be influenced either by some anions such as S , I , Br , which react with AgCl, or by change of the ionic strength. 

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