Michler’s thioketone

We proposed new photometric reagent 4,4 -bis(diethylamino)-thiobenzophenone (ethyl derivative of Michler s thioketone, EMT) for the determination of free chlorine and chloramines in drinking water. 

Stock solution Dissolve 1 g 4,4 -bis(dimethylainino)thiobenzophenone (Michler s thioketone) in 100 ml chloroform. 

The reaction has not been elucidated. Presumably Michler s thioketone reacts with organomercury compounds to yield intensely colored, mesomer-stabilized diphenyl-methane derivatives. 

When overoxidation takes place by using peracids, A-sulfonyloxaziridines have been proposed as selective and mild oxidizing agents411. Oxidation of Michler s thioketone with chlorine, resulting from the decomposition of chloroform, yielded a compound without sulfur in the molecule412. 

FIA system employing the preliminary retention of Cu (and Zn) on a Chelex-100 column, elution of the metal ions with 0.1 M HNO3 and reaction with zincon was applied in analysis of brass and tap water [14]. PAR was used to the determination of Cu in industrial effluents [15]. The application of the complex with Michler s thioketone to the determination of Cu (the detection limit of 0.8 g 1 ) has been reported [16]. 

Michler s Thioketone Reagent lb 154-157 Morgan-Elson Reagent lb 232-235... 

The group of necrosis-inducing CWA also includes primary, secondary, and tertiary arsines. These chemical compounds were also analyzed using TLC. Separation of mixtures of these arsines is not difficult, and they can be visualized using Michler s thioketone, iodine, dithizone, and a metacresol purple dye. Using the last reagent it is possible to detect lewisite at the level of 0.05 p,g per spot. ... 

Pantaler et al. [4] proposed a reactive indicator paper for semiquantitative active chlorine determination in potable water. The indicator paper was made by consecutive treatment of ordinary filter paper with EDTA and Michler s thioketone solutions. To determine active chlorine, a drop of water sample was added onto a strip of indicator paper and the color produced after a few seconds was compared with a color scale. With the stripes, active chlorine in the range of 0.1—3 mg/dm in drinking water samples could be estimated. 

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