Metrics holistic approach

As such, care must be taken when using the rate of consumption versus known reserves as a metric for the criticality of elements (Table 1.1). Importantly, in the case of many elements recycling rates are still low and as such a holistic approach to elemental use as catalysts must be adopted including processing, manufacture, recycling and substitution. ... 

The QMS and the processes that comprise it must be custom designed for the needs of the business. One size does not fit all situations. The requirements of an enterprise vary across sites and the phases of a product life cycle. A comprehensive system will ensure a holistic programmatic approach in its support to the enterprise. This does not mean that every phase of the product life cycle (discovery, development, commercial manufacturing) will utilize all the processes that comprise the system. Nor does it require that all commercial manufacturing sites will necessarily implement all processes. It does, however, provide a common platform and expectation for all processes, owners, metrics review programs, continuous improvement efforts, and the like when they are implemented. 

To overcome this limitation, a different approach can be used to start the metrification with the assumption of a systems thinking mindset and pursuing the conception of holistic metrics that can provide a global view of the chemical greenness for each case to be studied. This view should inelude all, or at least a large number, of the relevant greenness dimensions, along whieh the evaluation is made in parallel. 

This example shows that given a 10% final demand perturbation for both sectors, the resulting total inoperability for Sector 1 will be 19%, which is equivalent to a 190 loss in its total output. By the same token, the total inoperability for Sector 2 will be 13%, which is equivalent to a 260 loss in its total output. From this illustrative example, we have demonstrated that the ranking of key sectors may vary between the two metrics (i.e., economic loss vs. total inoperabiUty). A policymaker that puts more weight on inoperability will choose to prioritize Sector 1. On the other hand, the policymaker will opt to prioritize Sector 2 when economic loss is used as the sole criterion. Hence, a balanced approach that takes into consideration policymaker preferences across economic loss, inoperability, and other appropriate metrics will result in a more holistic method for key sector identification and prioritization. 

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