Methyltransferase genes

Relling MV, Hancock ML, Rivera GK, Sandlund JT, Ribeiro RC, Krynetski EY et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999 91[23] 2001-2008. 

Spire-Vayron de la Moureyre C, De-buysere H, Mastain B et al. Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population. Br J Pharmacol 1998 125 879-887. 

Spire-Vayron de la Moureyre C, Debuysere H, Sabbagh N, Marez D, Vinner E, Chevalier ED et al. Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis. Hum Mutat 1998 12 177— 185. 

Barnes, W. G., Grinde, E., Crawford, D. R., Herrick-Davis, K. and Hough, L. B. Characterization of a new mRNA species from the human histamine N-methyltransferase gene. Genomics S3 168-171,2004. 

McLeod, H.L., Siva, C. (2002) The thiopurine S-methyltransferase gene locus— implications for clinical pharmacogenomics. Pharmacogenomics. 3, 89-98. 

Sasaki, M., Kaneuchi, M., Sakuragi, N., and Dahiya, R. (2003) Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer. Cancer Res. 63, 3101-3106. 

Ibrahim, R.K. and Muzac, L, The methyltransferase gene superfamily a tree with multiple branches, in Evolution of Metabolic Pathways, Romeo, J.T., Ibrahim, R., Varin, L., and De Luca, V., Eds., Elsevier Science Ltd, Oxford, 2000, 349. 

Thiopurines in the Treatment of Childhood Acute Lymphoblastic Leukemia and Genetic Variants of the Thiopurine S-Methyltransferase Gene... 

Alves S, Amorim A, Ferreira F et al. Influence of the variable number of tandem repeats located in the promoter region of the thiopurine methyltransferase gene on enzymatic activity. Clin Pharmacol T/rer 2001 70 165-174. 

Hamdan-Khalil R, Gala JL, Allorge D et al. Identification and functional analysis of two rare allelie variants of the thiopurine 5-methyltransferase gene, TPMT 16, and TPMT 19. Biochem Pharmacol 2005 69 525-529. 

Lindqvist M, Aimer S, Peterson C et al. Real-time RT-PCR methodology for quantification of thiopurine methyltransferase gene expression. Eur J Clin Pharmacol 2003 59 207-211. 

Tenhunen J, Salminen M, Jalanko A, Ukkonen S, Ulmanen I. Structure of the rat catechol-O-methyltransferase gene separate promoters are used to produce mRNAs for soluble and membrane-bound forms of the enzyme. DNA and Cell Biology 1993 12 253-263. 

Freitag A, Rapp H, Heide L et al (2005) Metabolic engineering of aminocoumarins inactivation of the methyltransferase gene cloP and generation of new clorobiocin derivatives in a heterologous host. ChemBioChem 6 1411-1418... 

Freitag A, Li S-M, Heide L (2006) Biosynthesis of the unusual 5,5-gem-dimethyl-deoxysugar noviose investigation of the C-methyltransferase gene cloU. Microbiology 152 2433-2442... 

Yan L, Otterness DM, Kozak CA, Weinshilboum RM. Mouse nicotinamide N-methyltransferase gene molecular cloning, structural characterization, and chromosomal localization. DNA cell Biol. 1998 17(8) 639—667. 

Xu GL, Bestor TH, Bourch his D, Hsieh CL, Tommerup N, Bugge M, Hulten M, Qu X, Russo JJ, Yiegas-Pequignot E. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 1999 402 187-191. 

Hansen RS, Wijmenga C, Luo P, Stanek AM, Canfield TK, Weemaes CM, Gartler SM. The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome. Proc Natl acad Sci USA 1999 96 14412-14417. 

Narva KE, Van Etten JL, Slatko BE et al (1988) The amino acid sequence of the eukaryotic DNA [N6-adenine]methyltransferase, M. CviBIII, has regions of similarity with the prokaryotic isoschizomer M.TaqI and other DNA [N6-adenine] methyltransferases. Gene 74 253-259... 

Timinskas A, Butkus V, Janulaitis A (1995) Sequence motifs characteristic for DNA [cytosine-N4] and DNA [adenine-N6] methyltransferases. Classification of all DNA methyltransferases. Gene 157 3-11... 

SUZUKI, K YAMADA, Y, HASHIMOTO, T Expression of Atropa belladonna putrescine jV-methyltransferase gene in root pericycle. Plant Cell Physiol., 1999, 40,289-297. 

CROWELL, D. N., KENNEDY, M., Identification and functional expression in yeast of a prenylcysteine alpha-carboxyl methyltransferase gene from Arabidopsis thaliana., Plant Mol.Biol, 2001,45,469-476. 

IBRAHIM, R. K., MUZAK, I., The methyltransferase gene superfamily A tree with multiple branches, in Recent Advances in Phytochemistry Evolution of Metabolic Pathways (J. T. Romeo, R. I., Luc Varin, and V. De Luca, eds,), Elsevier Science Ltd., Oxford, 2000 pp. 349-384... 

Herken H, Erdal ME. 2001. Catechol-O-methyltransferase gene polymorphism in schizophrenia Evidence for association between symptomatology and prognosis. Psychiatr Genet 11 105-109. 

Ohmori O, Shinkai T, Kojima H, Terao T, Suzuki T, et al. 1998. Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics. Neurosci Lett 243 109-112. 

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