Methylsulfonic acid

Phenyl methyl ketone 1 was brominated to give l-phenyl-2-bromoethanone 2. Compound 2 was treated with methylsulfonic acid to yield the corresponding methylsulfonate 3. Etherification of 3 gave the a-benzyloxy derivative 4 and compound 4 was then chlorinated to give the 2,4-dichlorinated derivatives in both aromatic ring systems 5. Compound 5 reacted with imidazole in dimethylformamide to give miconazole 6 [7], which is converted to miconazole nitrate. 

Methyl succinyl chloride, ml95 Methylsulfonic acid, m34 Methyl theobromine, cl... 

Synthesis of the oxadiazolopyrimidone 358 was accomplished by reaction of the amide 357 with phosphorus pentoxide and methylsulfonic acid in low yield <1994PHA880>. Also, its benzologue 360 could only be obtained in very modest yield <2004TL8741> in the case, reaction of the benzonitrile derivative 359 with acetylhydrazine resulted in formation of the bicyclic product 360. 

Methylesculetol-6,7-dinicotinate (32) is useful as an antiinflammatory and vasodilator oflow toxicity (101). The synthesis of asarone [5555-15-1] (2,4,5-trimethoxy-l-propenylbenzene), which is used as a tranquilizer, has been patented (102). It occurs in calamus root, Acorns calamus L.y and is a chemosterilant for insects (103). 6,7-Dihydroxycoumarin-4-methylsulfonic acid and its salts are useful in the treatment of capillary permeability and fragility and for protecting oxidizable metabolites and drugs against biooxidation (104). Certain chromones derived from hydroxyhydroquinone, eg (33), and its salts, esters, and amides are valuable in the prophylactic treatment of asthma (105) (see Antiasthmatic agents). 2-Methoxy-6-multiprenyl-l,4-benzoquinones are intermediates in the microbiological synthesis of coenzyme Q compounds (106). 

Methylsuccinyl chloride, ml 88 methylsulfonic acid, m30 Methyl theobromine, cl 3-Methyl-2-thiabutane, il04... 

The methyl ester of methylsulfonic acid is methylmethane sulfonate. Its structural formula is... 

SYNS EMS ENT 26,396 ETHYL ESTER of METHANESULFONIC ACID ETHYL ESTER of METHYLSL LFONIC ACID ETHYL ESTER of METHYLSULPHONICACID ETHYL METHANE-SULPHONATE ETHYL METHANSULFONATE ETHYL METHANSULPHONATE HALF-MYLERAN METHYNESULPHONIC ACID ETHYL ESTER METHYLSULFONIC ACID, ETHYL ESTER NSC-26805 RCRA I tYISTE NUMBER U119... 

Acetoxy compounds from methylsulfonic acid esters with simultaneous dehydration Epimerization of steroids... 

Ethylene derivatives from methylsulfonic acid esters... 

Beilstein Handbook Reference) AI3-28532 BRN 1446024 CCRIS 2783 EINECS 200-898-6 HSDB 5004 Kyselina methansulfonova Methane-sulfonate Methanesulfonic acid Methanesulphonic acid Methylsulfonic acid MSA NSC 3718. Used as a polymerization catalyst, as a solvent, and in chemical synthesis. Solid mp B 20 bpio = 167 d = 1.4812 soluble in H2O. poorly soluble in organic solvents. Lancaster Synthesis Co. Uallinckrodt Inc. Sigma-Aldrich Fine Chem. 

Methyl succinate. See Dimethyl succinate Methylsulfonic acid. See Methanesulfonic acid... 

Sonochemical rearrangements are rare. The first case reported consists of the rearrangement of polycyclic hydrocarbons to ada-, dia-, and triamantane cage compounds (Eq. 75).223 The catalysts are usually superacids, such as trifluoro-methylsulfonic acid-antimony pentafluoride. 

Carboxyl methylsulfonic acid, ZnS04 French patent 1020 282... 

Exposure Test specimens were of AISI Type 316L. (UNS S31603) stainless steel (density 7.98 g/cm ), with dimensions of 25 x 50 x 3 cm (1 X 2 X % in.), immersed in 500 mL of 15 % methylsulfonic acid + 5 % sulfuric acid, balance water, at atmospheric pressure and 45°C. 

Fig. 11.16 A compound figure consisting of both experimental [75] and theoretical results [76], Lower Left Measured proton conductivities under dry conditions versus temperature of three monofunctionalized heptanes 1-heptylphosphonic acid (P-C7), magenta squares, 1-heptylsulfonic acid (S-C7), yellow triangles, and 2-heptylimidazole (I-C7), blue circles. Upper Right Computed energetic barriers for neat (i.e., acid to acid) proton transfer for methylphosphonic acid, magenta squares, methylsulfonic acid, yellow triangles, and methylimidazole, blue circles. The combined results suggest that proton conductivity is at least partially a function of the barrier for proton transfer the experimental proton conductivities are inversely related to the computed proton transfer barrier...

Good solvents for PBl are polar aprotic solvents such as iV,A/-dimethylacetamide (DMAc), A -methyl-2-pynolidOTie (NMP) or dimethylsulfoxide (DMSO), and strmig protic acids like phosphoric acid, sulfuric acid (risking sulfonation reactions), or methylsulfonic acid. In order to dissolve PBl in organic solvents, great care must be taken to remove all phosphoric acid traces from the polymer, since it strongly hinders dissolution in DMAc. 

Methylsulfonic acid 6744 1 -Naphthol-4-sulfonic acid 6121 3-Nitrobenzyl alcohol 8062... 

Methyl sulfate) see Dimethyl sulfate (Methyl sulfide) see Dimethyl sulfide (Methylsulfonic acid) see Methanesulfonic acid (Methyl sulfoxide) see Dimethyl sulfoxide Methyl trichlorosilane (Trichloromethylsilane) Methyltriglycol (Triethylene glycol monomethyl ether) (2-Methyl-1,5-valerodinitrile) see 2-Methylglutaronitrile... 

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