Methylene bis-acrylamide

Solubilization of vinylpyrrolidone, acrylic acid, and A,A -methylene-bis-acrylamide in AOT-reversed micelles allowed the synthesis in situ of a cross-linked polymer with narrow size distribution confined in the micellar domain. These particles displayed high entrapment efficiency of small hydrophilic drugs and have been considered interesting drug delivery systems [239],... 

Vinylphenyl-terminated PBE dendrons were prepared as polymerizable den-drons from 4-vinylbenzyl chloride [37]. The vinylphenyl-terminated PBE dendrons are useful to make the lanthanide-cored dendrimer complexes polymerizable. The Ist-generation Tb +-cored dendrimer complex bearing the vinyl-phenyl terminal on the dendron subunits (Fig. 5) was copolymerized with N-iso-propylacrylamide in the presence of methylene bis-acrylamide (as crosslinker) in DMSO to give a green-luminescence transparent gel. The DMSO gel was con-... 

Morpholine Methylene-bis-acrylaiuide Figure 1-2. Morpholine, methylene-bis-acrylamide. 

A fluid loss additive for hard brine environments has been developed [1685], which consists of hydrocarbon, an anionic surfactant, an alcohol, a sulfonated asphalt, a biopolymer, and optionally an organophilic clay, a copolymer of N-vinyl-2-pyrrolidone and sodium-2-acrylamido-2-methylpropane sulfonate. Methylene-bis-acrylamide can be used as a crosslinker [1398]. Crosslinking imparts thermal stability and resistance to alkaline hydrolysis. 

Polyacrylamide gel is the most commonly used type of support medium for gel electrophoresis, and polyacrylamide gel electrophoresis is simply known as PAGE. The gel is usually formed by polymerization of acrylamide and the cross-linking agent N, iV -methylene-bis-acrylamide (Bis) in the presence of ammonium persulfate (APS, initiator) and N, N, N, iV -tetramethyl-ethylenediamine (TEMED, accelerator). The total concentration of acrylamide... 

Polyacrylamide shows many advantages over starch gel as a medium for high resolution electrophoresis and because of its synthetic nature its pore size can be more easily controlled. The gel is formed by the polymerization of the two monomers, acrylamide and a cross-linking agent, N, iV-methylene-bis-acrylamide (Figure 3.26). The proportion of the two monomers and not their total concentration is the major factor in determining the pore size, the latter having more effect on the elasticity and... 

The first hydrophilic monoliths based on acrylamide chemistry were based on copolymerization of acrylic acid and (V,/V -methylene bis(acrylamide) in the presence of an aqueous buffer as porogen [66], Shortly after, the first hydrophobic capillary support for hydrophobic interaction chromatography was fabricated by the substitution of acrylic acid by butyl methacrylate, whereas the monomer... 

Suedee R, Seechamnanturakit V, Canyuk B, Ovatlampom C, Martin GP. Temperature sensitive dopamine-imprinted (iVJV-methylene-bis-acrylamide cross-linked) polymer and its potential application to the selective extraction of adrenergic drugs from urine. J Chromatogr A 2006 1114 239-249. 

Wet cells (15g) in saline (80 ml) are mixed with an equal volume of a 10% w/v monomer solution (85% acrylamide/15% NN methylene bis-acrylamide). Initiator is added (1 ml 5% NNN N -tetramethyldiethylamine and 4 ml 5% ammonium persulphate). Gelation occurs within 20 minutes at 5°C. 

Chemical reactions illustrating the copolymerization of acrylamide and N,N -methylene-bis-acrylamide. See text for details. 

Acrylamide, A, A, A 1, A -tetramethylethylenediamine, 7V,7V -methylene-bis-acrylamide, and ammonium persulfate are toxic and must be used with care. Acrylamide is a neurotoxin, a cancer suspect agent, and a potent skin irritant, so gloves and a mask must be worn while handling it in the unpolymerized form. 

See Problem 1. Increase the percent of cross-linking agent, methylene bis acrylamide, in the gel. 

Time Tilon Polyamide Methylene bis-acrylamide Solid ... 

The kinetics of AA and N,N -methylene-bis-acrylamide polymerization with varied contents of monomers (up to 15 carrier wt%) on a magnetite surface at different values of emitter power was studied. The analysis of kinetic curves obtained by monomer residue titration in non-aqueous medium (methanol) indicates that complete polymerization of the biocompatible layer of selected mass is reached in 2 min. 

An environmentally responsive, hydrogel microsphere coated with a lipid bilayer has recently been shown to act as a secretory granule mimic (Figure 16.5). Methylene-bis-acrylamide/methacrylic acid... 

Polyacrylamide gels are formed as the result of polymerization of acrylamide (monomer) and AT,AT-methylene-bis-acrylamide (cross-linker) (Fig. 4-5). The acrylamide monomer and cross-linker are stable by themselves or mixed in solution, but polymerize readily in the presence of a free-radical gen-... 

Dissolve 29.2 g of acrylamide and 0.8 g of N,W -methylene-bis-acrylamide in 100 ml of distilled water. Filter through a 0.45-/xM-pore-size membrane (to remove undissolved particulate matter) and store in a dark bottle at 4°C. 

These workers also devised a new photosensitizing system for mixtures of acrylamide and methylene bis-acrylamide, a crosslinking agent (47). Ferric ion and t-butylhydroperoxide are added to the mixture, providing high sensitivity (20 mJ/cm ) from the uv out to 500 nm. The postulated initiation sequence is... 

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