Hydrogel microsphere

Soppimath, K.S., Kulkarni, A.R. and Aminabhave, M. (2000) Controlled release of antihypertensive drug from the interpenetrating network poly (vinyl alcohol)-guar gum hydrogel microspheres. Journal of Biomaterials Science-Polymer Edition, 11, 27-43. 

The preparation of monodisperse hydrogel microspheres, such as poly-acrylam-ide-co-acrylic acid, poly(N-isopropylacrylamide-co-acrylic acid), has been performed for drug devices thanks to their biocompatibility [77, 79]. The average diameters of the microspheres were dependent on the pore sizes (from 0.33 to 1.70pm) of SPG membranes used in the preparation procedure. 

An environmentally responsive, hydrogel microsphere coated with a lipid bilayer has recently been shown to act as a secretory granule mimic (Figure 16.5). Methylene-bis-acrylamide/methacrylic acid... 

In general, microgels obtained by radiation methods can be used in various applications in the same way as conventional synthesized systems, e.g., as drug delivery templates, for encapsulation, or as microreactors [29, 30], PAAm for example can be used as template material to synthesize hollow cadmium selenide nanospheres [24], and PVP can be used for the incorporation of ferromagnetic nanoparticles to obtain magnetic hydrogel microspheres [13],... 

Kawaguchi H, Fujimoto K, Mizuhara Y (1992) Hydrogel microspheres III Temperature-dependent adsorption of proteins on poly-iV-isopropylacryamide hydrogel microspheres. Colloid Polym Sci 270 53-57... 

Kondo, A., and Fukuda, H., Preparation of thermo-sensitive magnetic hydrogel microspheres for antibody and application to enzyme immobilization, J. Ferment. Bioeng., 41, 99, 1994. 

A number of general reviews on polyphosphazenes have appeared. Specific reviews on polyphosphazenes deal with radiation graft polymerization, anionic polymerization, hydrogel microspheres,controlled biodegradability,coatings, and membrane separation. 

Multicomponent, environmentally responsive, hydrogel microspheres, coated with a lipid bilayer, can be used to mimic the natural secretory granules for drug delivery. 

Park JY, Oh HJ, Kim DJ, Back JY, Lee SH (2006) A polymeric microfluidic valve employing a pH-responsive hydrogel microsphere as an actuating source. J Micromech Microeng 16 656-663... 

YIN Yin, X. and Stoever, H.D.H., Hydrogel microspheres by thermally induced coacervation of poly(A/,A/ -dimethylaciylamide-co-glycidyl methaciylate) aqueous soXviAoas, Macromolecules, 36, 9817, 2003. 

Y. Senuma, C. Lowe, Y. Zweifel, J. G. Hilborn, and I. Marison. Alginate hydrogel microspheres and microcapsules prepared by spinning disk atomization. Biotechnology and Bioengineering, 67(5) 616-622, 2000. 

Senuma, Y. Lowe, C. Zweifel, Y Hilborn, J.G. Marison, I. Alginate hydrogel microspheres prepared by spinning disk atomization. Biotechnol. Bioeng. 2000, 67 (5), 616-622. 

Nagae, M., Ikeda, T., Mikami, Y., Hase, H., Ozawa, H., Matsuda, K., Sakamoto, H., Tahata, Y., Kawat,a M., Kubo, T. 2007. Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres. Tissue Eng 13(1), 147-158. 

Kajjari, P B., Manjeshwar L. S., andAminabhavi, T. M. Novel interpenetrating polymer network hydrogel microspheres of chitosan and poly(acrylamide)-grafted-guar gum for controlled release of ciprofloxacin. Ind. Eng. Chem. Res., 50, 13280-13287 (2011). 

Soppimath, K. S. and Aminabhavi, T M.. Water transport and drug release study from cross-hnked polyacrylamide grafted guar gum hydrogel microspheres for the controlled release apphcation. Eur. J. Pharm. Biopharm., 53,87-98 (2002). 

Y. Sato, S. Ikegaki, K. Suzuki, H. Kawaguchi, Hydrogel-microsphere-enhanced surface plasmonresonance for the detection of a K-ras point mutation employing peptide nucleic acid, J. Biomater. Sci. -Polym. Ed. 14 (2003) 803-820. 

Singh, M., Rafhi, R., Singh, A., Heller, J., Talwar, G. P., and Kopecek, J., 1991b, Controlled release of LHRH-DT from bioerodible hydrogel microspheres, Int J. Pharm. 76 R5-R8. 

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