Mono methylamine

See Methyl methacrylate monomer also Mono-methyl amine (Methylamines)... 

Dichloro-s-triazine and its 6-alkyl analogs are as easily hydrolyzed by water as trichloro-s-triazine and, on suspension in aqueous ammonia (25°, 16 hr), the first is diaminated in good yield. 2,4-Bistrichloromethyl-6-methyl- and -6-phenyl-s-triazines (321) require a special procedure for mono-alkoxylation (0-20°, 16 hr, alcoholic triethylamine) disubstitution occurs at reflux temperature (8 hr). Aqueous triethylamine (100°, 3 hr) causes complete hydroxy-lation of 2,4,6-tris-trichloromethyl-s-triazine which can be mono-substituted with ammonia, methylamine, or phenoxide ion at 20°. 

Simultaneous Differential Thermal-Mass Spectrometer Analysis of Nitrate Salts of Mono-methylhydrazine and Methylamine , SAMSO TR-70-117(1970) 54) Anon, Propellants,... 

Aminolysis of PET involves the reaction of PET with primary amines such as methylamine, ethylamine, and ethanolamine37 at temperatures in the range of 20-100°C to form the mono- and diamides of TPA. 

As already reported in Table 6, the solubility of phosphazene polymers is strongly influenced by the nature of the substituent groups attached at the phosphorus atoms along the -P=N- skeleton. Water-solubility, for instance, can be induced in polyphosphazenes by using strongly polar substituents (e.g. methylamine [84], glucosyl [495], glyceryl [496], polyoxyethylene mono-methylether [273] or sulfonic acid [497,498] derivatives), or may be promoted by acids or bases when basic (amino substituents like ethylamine [499]) or acid (e.g. aryloxy carboxylate [499] or aryloxy hydroxylate [295]) substituents are exploited. 

The action of diazomethane in aqueous 1,2-dimethoxyethane on 4-methoxy-l-/3-D-ribofuranosyl-2(lf/)-pyrimidinone gave, after purification, the corresponding 2 -methyl ether in 37% yield.333 N.m.r. spectroscopy showed that the crude mono-O-methyl fraction contained the 2 - and 3 - isomers in the ratio of 7 2. The 2 -methyl ether proved to be a versatile intermediate, as acid hydrolysis yielded 2 -0-methyluridine, whereas reaction with ammonia or methylamine... 

The previous review1 has treated in detail only the following amines methylamine, dimethylamine, trimethylamine, 2-aminoethanol, ethylenediamine, nitroguanidine and similar ones. In the period of the present review, some simple molecules of interest have been treated such as the aminoethanol series, including mono-, di- and tri-substituted derivatives, as well as a number of derivatives of guanidine. These will be dealt with for purposes of internal comparison. 

In a study of detonation of aqueous solutions of perchlorate salts of hydroxy lamine, urea, methylamine and diaminoethane (mono- or di-salts), the former could be detonated in 20-25% solution at 407-587°C. 

The products obtained from these condensations are predictable for simple mono-functional substrates primary amines usually form compounds where two equivalents of primary nitramine are incorporated into the product (Equation 5.19), whereas simple secondary amines can only combine with one equivalent of nitramine (Equation 5.20). The bis-nitramine (185) is formed from the reaction of methylamine with two mole equivalents each of methyl-nitramine and formaldehyde. 

Dinitro[l,8]naphthyridine and its 2-substituted derivatives are dehydro-methylaminated with a solution of potassium permanganate in liquid methylamine to afford the corresponding mono- or bis-methylamino-3,6-dinitro[l,8]naphthyridines (Scheme 7) <2000CJC950>. When the 2-substituent is either chlorine or OMe, then some substitution by NHCH3 also occurs. Quantum-chemical calculations have shown that the reaction is controlled by the interaction of the frontier MOs. 

A more convergent synthesis of frovatriptan using the methylamino-substituted cyclohexanone equivalent 75 is shown in Scheme 25.° The mono-ketal of 1,4-cyclohexanedione (74) was treated with methylamine in ethanol and then hydrogenated to give 75 as an oil, which was converted to the hydrochlonde salt. The hydrazine of 76, formed in situ by treatment with sodium nitrite followed by reduction of the diazonium salt with sodium dithionite, was reacted with 75 and additional concentrated HCl at 70 °C to deliver racemic frovatriptan (rac-6). 

C4Hx 2N203 mw 136.2 N 20.57% OB to C02 —129.22% white or colorl crysts mp 325—28° (Ger sources), 405—10° (Fr sources) d 1.25 g/cc, 0.70g/cc (bulk). Sol in hot w si sol in cold w. Not an expl by itself, TeMeAN forms powerful expls, acting as a fuel when mixed with oxygen carriers such as nitrates (see below). It was produced in Ger in the last part of WWII, where it was used as an expl extender when the shortage of other expls (such as RDX, TNT, etc) became very acute. Two methods were used for its manuf (see below), one consisted of the interaction of methyl nitrate with trimethyl-amine (which was obtd together with mono-methylamine in the manuf of dimethylamine), and the other method was the interaction of am-... 

Methylamines are produced by reacting gaseous methanol with a catalyst at 350 to 400°C and 290 psi (2.0 MPa), then distilling the reaction mixture. Any ratio of mono-, di-, or trimethylamines is possible by recycling the unwanted products. 

Figure 1. Yield of pentasil zeolites (percentage crystallization) as a function of time. Abbreviations are C, for mono-n-butylair ne, CU for mono-n-propylamine, C2 for mono-n-ethylamine, C. for mono-n-methylamine, di-C, for di-n-propylamine, di-C, for di-n-propylamine,+di-C2 for di-n-ethylamine, di-n-C.. for di-n-methylamine, TPA Al-free for the aluminium-free synthesis with the tetrapr pylammonium cation, TPA for tetrapropylammonium cation, TEA Al-free for the+aluminium-free synthesis with the tetraethylammonium cation, TEA for tetraethylammonium cation and tri-C for tri-n-propylamine.

Kvaerner Process Technology N-methyl pyrrolidone Mono methylamine, gamma butyrolactone Uses a proprietary reactive distillation process to reduce capaital costs and improces product quality NA NA... 

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