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Methyl scopolamine

N-butyl-scopolamine (BuS) cimetropium (Cim) ipratropium (Ipra) N-methyl-scopolamine (MeS)... [Pg.291]

Callegari et al. characterized the central nervous system (CNS) penetration of the QTA trospium and methyl scopolamine as well as of the TTA scopolamine [77], Therefore, they performed in vivo studies administering the drugs to rats subcutaneously. After 1 h animals were euthanized, cerebrospinal fluid (CSF) was taken from cistema magna and brains were removed and homogenized. Whereas CSF was mixed with IS (atropine) to be directly injected for LC-ESI MS/MS analysis, brain homogenates were extracted by SPE on Oasis HLB material subsequent to IS... [Pg.333]

Coimnon Name Methyl scopolamine Common Name Nethscopolamine bromide Common Name Famine (bromide)... [Pg.108]

BZ (7.4 - 14.5 pg/kg) aerosol Inhalation, 2 subjects 3834 (2 0 mg) percutaneous, 1 subject Atropine (125 pg/kg) Intramuscular, 3 subjects Prolixin (15.0 - 23.0 pg/kg) Intramuscular, 6 subjects 302668 (10.0 pg/kg) Intravenous, 1 subject 302196 (75.6 Pg/kg) oral, 1 subject TAB (90 mg total) Intramuscular, 1 subject Pretreatment with methyl scopolamine (1.0 mg) 1 subject Only 2 subjects (AlOJ) and (AlOK) who received doses of BZ and were subsequently treated with physostlgmine, showed any prolonged central effects (hallucinations, disorientation, confusion) lasting 4 to 6 days post >exposure Both subjects were asymptomatic and appeared normal when discharged from test. One subject (AlCM)) was exposed to Prolixin (23.0 pg/kg) and then treated with multiple doses (1.0 mg X 7 doses) over a 2 ay period, intramuscularly At 27 hours post-exposure, the subject complained of blurred vision, and facial expression was mask-llke, tongue "thick" and jaws open. [Pg.118]

Burdo analyzed methyl scopolamine using sodium decylsulfate as ion-pairing reagent. Walters... [Pg.250]

Hartmann continued the work started by Burdo, mentioned above, and used sodium decylsulfate and dioctylsulfosuccinate as ion-pairing reagents in the analysis of methyl scopolamine... [Pg.250]

Simultaneous homatropine, methscopolamine, tropic acid, atropine methyl, scopolamine... [Pg.176]

See other pages where Methyl scopolamine is mentioned: [Pg.128]    [Pg.244]    [Pg.227]    [Pg.149]    [Pg.287]    [Pg.300]    [Pg.334]    [Pg.339]    [Pg.340]    [Pg.259]    [Pg.70]    [Pg.80]    [Pg.247]    [Pg.252]    [Pg.29]    [Pg.258]    [Pg.551]    [Pg.1947]    [Pg.112]   
See also in sourсe #XX -- [ Pg.250 , Pg.251 , Pg.254 ]



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