2-Methyl-2-phenylpropane

Synonym (l,l-dimethylethyl)benzene, 2-methyl-2-phenylpropane, trimethylphenylmethane, pseudobutylbenzene, t-butylbenzene... 

Methyl phenyl ether, m55 Methyl phenyl ketone, a31 2-Methyl-2-phenylpropane, b523 Methyl y-picolinate, m413... 

Synonyms AI3-00118 BRN 1421537 -BuBz er -BuBz -Butylbenzene tertiary-Bu y -benzene (l,l-Dimethylethyl)benzene EINECS 202-632-4 2-Methyl-2-phenylpropane NSC 6557 2-Phenyl-2-methylpropane Phenyltrimethylmethane Pseudobutylbenzene Trimethylphen-ylmethane UN 2709. 

Methyl-l-phenylpropane, see Isobutylbenzene 2-Methyl-2-phenylpropane, see ferf-Butylbenzene Methyl phthalate, see Dimethyl phthalate... 

The elimination of the hydridopalladium group to the allylic position causes the formation of 3-substituted carbonyl compounds when allylic alcohols are reacted with organic halides (39). For example, when iodobenzene is reacted with methallyl alcohol, 2-methyl-3-phenylpropanal was formed in 91% yield along with 4% of 2-methyl-2-phenylpropanal ... 

We do not know if the vinylic alcohol is actually an intermediate or whether a hydride-71 complex of it rearranges directly to the aldehyde as probably happens in the palladium-catalyzed oxidation of ethylene to acetaldehyde. The formation of 4% 2-methyl-2-phenylpropanal is unexpected. This product must arise from a reversed addition of the phenylpalladium group followed by a hydrogen transfer from the hydroxyl-bearing carbon to the palladium, followed by reductive elimination of a hydridopalladium group. An alkyoxypalladium intermediate has been proposed (39). 

Methyl-2-phenylpropane, b425 Methyl y-picolinate, m402 Methylpiperidinol, hi 44 Methyl pivalate, m227... 

The 2-methyl-3-phenylpropanal is 90% pure by GLC. The product mixture contains 6% of another isomer, 2-methyl-2-phenylpropanal, and a small amount of 2-phenyl-2-propen-l-ol. A completely pure sample of the aldehyde is readily obtained by stirring the crude aldehyde with excess saturated aqueous sodium bisulfite solution for several hours, filtering the solid bisulfite adduct, washing with ether, and liberating the aldehyde with excess aqueous sodium bicarbonate. Redistillation gives the completely pure aldehyde in about 60% yield. 

Carbene (or carbenoid), generated via reaction of lithium diisopropylamide with 1,1-di-chloro-2-methyl-2-phenylpropane, did not form a 1,3-C-H insertion product, but yielded an alkene, via 1,2-Ph migration, instead. ... 

Synonyms (1,1-Dimethylethyl) benzene 2-Methyl-2-phenylpropane Pseudobutylbenzene T ri methyl phenyl methane... 

Methyl-2-phenylpropane. See t-Butylbenzene 2-(4-Methylphenyl)-2-propanol. See Tri methyl benzyl alcohol 2-Methyl-3-phenyl-2-propenal. See a-Methylcinnamaldehyde 2-(p-Methylphenyl) propene. See p-a-Di methylstyrene... 

There are three major limitations on the Friedel-Crafts alkylation. The first is the possibility for rearrangement of the alkyl group. Friedel-Crafts alkylation generates a carbocation, and as we have already seen in Section 6.3C, carbocations may rearrange to a more stable carbocation. For example, reaction of benzene with l-chloro-2-methylpropane (isobutyl chloride) gives only 2-methyl-2-phenylpropane (tert-butylbenzene). 

The reaction of 2-methyl-2-phenylpropanal and GaCl3 gave a rearranged phenyl isopropyl ketone, in which phenyl migration proceeded to the carbonyl carbon as induced by GaCls (Scheme 7.25) [47]. Imidazolyl chloride was used as the acid... 

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