Methyl-perfluorooctanoate

The preferred process consists of mixing sulfuric acid, methanol, and the fluori-nated emulsifier liquid resulting in a strongly acidic mixture containing the methyl ester of the perfluorinated emulsifier acid, that is, methyl perfluorooctanoate (Me-PFOA). Distillation of Me-PFOA yields a ternary mixture containing Me-PFOA along with water and methanol. Condensation of the vapor results in two phases. The lower phase is more or less pure ester while the upper phase consists of water... 

Another uncertainty in the children s MOE analysis is that the biomonitoring data showed that perfluorooctanoates related to PFOA—per-fluorohexansulfonate and N-methyl perfluorooctanesulfonamidoacetate— were considerably higher in children than in adults. The reason is unknown, but the original authors suggest that it may reflect a different exposure pattern in children (Olsen et al. 2004). Toxicology and exposure data on these analytes are not sufficient to enable a separate risk assessment to evaluate the children s exposures. 

Methyl trifluoromethane sulfonate 206-376-4 C-1095 Capric acid Emery 659 Emery 6359 NAA-102 Prifrac 2906 Unifat 10 206-392-1 Perfluoroheptane PF-5070 206-397-9 Fluorad FC-26 Perfluorooctanoic acid 206-478-9... 

Perfluoroammonium octanoate. See Ammonium perfluorooctanoate (Perfluoro-n-butyl) methyl ether. See Methyl nonafluorobutyl ether Perfluorobutyric acid. See Heptafluorobutyric acid Perfluorocaprylic acid. See Perfluorooctanoic acid Perfluorocaprylic acid ammonium saK. See Ammonium perfluorooctanoate Perfluoroctanoic acid. See Perfluorooctanoic acid Perfluoroethylene propylene. See Fluorinated ethylene/propylene Perfluoroheptane... 

The direct determination of fluorinated surfactants is possible if the fluorinated surfactant is amenable to chromatography or spectroscopy. Belisle and Hagen [46] determined perfluorooctanoic acid in blood, urine, and liver tissue. Perfluorooctanoic acid was extracted from blood or other biological samples with hexane in the presence of hydrochloric acid and converted to its methyl ester with diazomethane. The recovery of known amounts of perfluorooctanoic acid added to human plasma was essentially quantitative. The precision of the method was inferior to that of the determination of perfluorooctanoic acid by elemental fluorine analysis but could probably be improved by using a capillary chromatographic column instead of the packed column used by the authors. 

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