Metal cation-carbohydrate complexes cations

S. R. Sarfati and P. Szabo, Quantitative determination with periodate of compounds subject to non-Malapradian oxidation. Part III. Cyclohexanehexols, Carbohydr. Res., 11 (1969) 571-573. S. J. Angyal, D. Greeves, and V. A. Pickles, The stereochemistry of complex formation of polyols with borate and periodate anions, and with metal cations, Carbohydr. Res., 35 (1974) 165-173. 

Complexes of metal cations with carbohydrates in solution, 47, 1 -43 Courtois, Jean Emile, obituary of, 49,11 -18 Cyclomalto-oligosaccharides(cyclodextrins), inclusion complexes of, 46, 205-249 addendum to, 46, 333-335... 

Macrostructure of mucus glycoproteins in solution, 47, 345-381 Metal cations, complexes of, with carbohydrates in solution, 47, 1 -43 Molecular structure of lipid A, 50,211 -276 Monosaccharides, decomposition of, 47, 203-278... 

Adducts prepared in aqueous media generally possess one or more molecules of water of hydration per molecule, the number being a function of cation, anion, and the combining ratio of carbohydrate to salt. Available data on complexes of simple carbohydrates indicate that three molecules of water per molecule may be the maximum for adducts of alkali metal salts as many as seven have been reported for those of the alkaline-earth metal salts. Most complexes, however, possess only one or two molecules per molecule. Generally, the higher the combining ratio, the smaller is the number of water molecules that can be accommodated by a molecule of the adduct. 

It was in 1971, just 100 years later, that there appeared the first paper to discuss the relationship between structure and complex-formation of neutral carbohydrates with cations. Most of the developments during the intervening 100 years were covered in an article by Rendleman in this Series. The present discussion is an updating of Rendleman s chapter, and it covers the renaissance of interest in metal - sugar complexes. The information given by Rendleman will not be repeated here unless it is required for the understanding of subsequent developments. 

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