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Metadate CD

Absorption - Rapidly and well absorbed from the Gl tract, methylphenidate achieves peak blood levels in 1 to 3 hours. Peak plasma levels occur in children in 4.7 hours for the SR tablets and 1.9 hours for the regular tablets. Mean times to reach peak plasma concentrations across all doses of Concerta occurred between 6 and 10 hours. Plasma half-life for Metadate CD is reportedly 6.8 hours. SR and ER tablets are more slowly but as extensively absorbed as regular tablets. [Pg.1154]

Brand Name(s) Concerta, Metadate CD, Metadate ER, Methylin, Methylin ER, Ritalin, Ritalin LA, Ritalin SR... [Pg.787]

The recently introduced product Concerta is a once-a-day administration MPH delivery system called OROS (osmotically released). This delivery system creates an ascending plasma level pattern instead of the peak-and-valley pharmacokinetic profile seen in the IR preparations. Similar extended-delivery bead-technology, double-pulse preparations have been introduced for Metadate-CD at 10, 20, and 30 mg (Green-hill et ah, 2002, in press) for the spheroidal technology of Ritalin-EA, and for Adderall-XR preparations (McGough et ah, 2002, in press). Beaded stimulant preparations mix IR and delayed-release beads in a capsule. The patient can swallow the capsule whole or sprinkle the contents in food if pill taking is difficult for the child. [Pg.257]

Metadate-CD, Ritalin-LA, Focalin, others Dexedrine 5 mg t 5, 10, 15 mg sustained-release spansules Adderall 5, 10, 20, 30 mg... [Pg.757]

Metadate CD ADHD Persons >6 years old start at 20 mg qam increase by 10-20 mg/day at weekly intervals as needed to attain response. [Pg.179]

Methylphenidate Ritalin-SR Ritalin LA Metadate ER Metadate CD Concerta Slowly absorbed tablet Capsule with 50% methylphenidate dose as immediate-release beads and 50% as delayed-release beads Slowly absorbed tablet with methylphenidate incorporated in a wax matrix tablet, allowing gradual diffusion Capsule that provides 30% of methylphenidate dose hy immediate-release beads and 70% of the dose by extended-release beads Tablet that contains approximately 22% of the methylphenidate dose in an immediate-release capsule overcoat and 78% within the tablet that is released by an osmotic process over an extended period... [Pg.185]

Diffucaps Eurand Povidone, HPMC, ethyl cellulose Combination of immediate and sustained release Metadate CD... [Pg.345]

Ritalin LA and Metadate CD (up to 8 hours duration of action) initial 20 mg once daily dosage may be adjusted In weekly 10 mg increments to a maximum of 60 mg/day taken in the morning... [Pg.123]

The newer sustained release Metadate CD has an early peak and an 8-hour duration of action... [Pg.123]

Metadate CD and Ritalin LA are somewhat similar to each other, both with an early peak and duration of acfion of abouf 8 hours... [Pg.126]

Metadate CD and Ritalin LA may be preferable for those ADHD patients who lose their appetite for dinner or have insomnia with Concerta... [Pg.126]

Trade names Centedrin Concerta Daytrana Metadate CD (Celltech) Methylin (Mallinckrodt) Rilatine Ritalin (Novartis) Rubifen... [Pg.373]

Drug delivery systems of once-daily products (Concerta, Metadate CD, Ritalin LA, Adderall XR) provide 8 to 12 hours of symptom control. Concerta uses an oral osmotic (OROS) controlled-release delivery system, while other preparations use combinations of immediate-release or extended-release beads containing drug. Concerta is a nondeformable tablet and it should not be given to children with gastrointestinal narrowing due to the risk of obstruction. Older wax-matrix sustained-release products (e.g., Ritalin SR)... [Pg.1134]

CCRIS 6258 Centedrin Centedrine EINECS 206-065-3 Meridil hydrochloride Metadate CD Methylin Methylphenidate hydrochloride Methylphenidylacetate hydrochloride Metilfenidat hydrochloride NSC 169868 Ritalin Ritalin hydrochloride. CNS, psychomotor stimulant. Crystals mp = 224-226° soluble in H2O, EtOH, CHCI3 LD50 (mus orl) = 190 mg/kg. CIba-Geigy Corp. [Pg.411]

See other pages where Metadate CD is mentioned: [Pg.637]    [Pg.638]    [Pg.640]    [Pg.1153]    [Pg.787]    [Pg.261]    [Pg.449]    [Pg.453]    [Pg.731]    [Pg.731]    [Pg.172]    [Pg.176]    [Pg.184]    [Pg.184]    [Pg.223]    [Pg.45]    [Pg.121]    [Pg.663]    [Pg.663]    [Pg.1136]    [Pg.1139]    [Pg.999]   
See also in sourсe #XX -- [ Pg.121 ]



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