Merck products

Chemiker sind der Zelle auf der Spur, Handelsblatt, August 2000 Plant cells as model for micro-reactor development availability of micro-flow devices German leadership first production applications BASF s motivation spotting for DNA arrays materials for micro reactors Merck production plant smallness for efficiency, but not an end in itself [232],... 

The electrode active masses were prepared by mixing the active material with 10 wt.% of polyvynilidene fluoride slurred in 1-methyl-pyrrolidone solvent. The actual mass was then pasted onto one side of precleaned Co foil, dried for 4 h at 100°C, pressed and the disks of 15,6 mm diameter were cut and placed into the cell s coins. Large excess of Li metal (foil) was used as a counter electrode. 1M LiPF6 solution in mixture of ethylene carbonate (50 vol.%) and methyl carbonate was used as an electrolyte (Merck product LP30). 

Different methods for scale-out have been collected and presented (Lob et al. 2006a). The two main methods are a smart scale-up, at best after having intensified the process, or the internal numbering-up concept. The first route was shown long ago by the Merck production case for an organometallic reaction, changing from micro- to mini-mixers (Krummradt et al. 2000). This route seems to be feasible, as long as... 

Fig. 26. Thermal decomposition of natural and synthetic hydrozincite. 1) Good Springs, USA 2) Durango, Mexico 3) Santander, Spain 4) Synthetic from zinc-hydroxide 5) Merck-product...

Hydrogen was purchased from Air Liquide it was passed over a catalytic purifier (type R 311 from BASF) and dehydrated over 5A molecular sieve at room temperature. Benzene was a Merck product, distilled and stocked over sodium. 

PVA (Merck) with molecular weight of 72,000 and degree of saponification of 98.5-99.2%, was used as supplied, AN (Merck) was purified by reduced pressure distillation. Ceric ammonium nitrate (CAN) (Merck) was used after vacuum drying. Acetic acid (Merck), dimethylformamide (DMF) and dimethylsulfoxide (DMSO) (Merck) were used without further purification. Other reagents used in the study were also all Merck products. 

E. Merck s Aimual Report on the Advancements of Pharmaceutical Chemistry and Therapeutics (1887-1940). English, French, Spanish, Portuguese, and It an (1930) editions. Contains original articles of general and scientific interest, a pharmacothera-peutic review, and medical opinions regarding E. Merck products. Originally a translation of E. Merckxs Jahresbericht but later a different and more popular publication. 

High viscosity is the main drawback for cholesteric liquid crystalline polymers in applications. However, cholesteric polymers have their advantages. They may exhibit the memory effect. These polymers make processing and handling easily. Therefore, cholesteric liquid crystalline polymers have become the new materials for optical filters, temperature indicators, etc. The Merck product with the trade name Transmax is actually associated with the cholesteric liquid crystalline polymers. 

For the Merck production case with the enolate synthesis performed as a microprocess step, flve parallel minimixers were sufficient [59]. For a polyacrylate pilot plant, 28 interdigital micromixers were connected, grouped into four groups each with eight micromixers [60]. 

Figure 9.34 Merck production plant for Grignard-based enolate formation (by courtesy of Springer) [68].

Produced by Sneptomyces nt murilts Merck product. Ivermectin, is approved for veterinary use as an antiparasitk has also been used to treat human tmchocerciaisis (river blindness). 

Produced by Streptomyces lactamdu-rniu Merck product, Producil, is... 

Merck product, Primaxin. is a very broad spectrum semisymhetic thienamycin derivative combined with cilastalin, which prevents renal metabolism by inhibiting dehydtopeptidase-l,... 

Merck product, Crixivan, is a newly approved (1996) HIV-1 proteinase inhibitor for use in treatment of AIDS. 

Merck product, Mcvacor, is approved for used in hypercholes-teiolemia. 

DNA gyrase inhibitot Merck product. Noroxin, claimed 1.3% of 1991 world market as sixteenth leading antibiotic orally administered and very broad spectrum of activity. 

Cellular proton-pump inhibitor Ascra/Merck product, Prilosec, has recently been approved for combination therapy with clarithromycin for treatment of Helicobacter pylori infections. 

Characteristic product of penicillin degradation Merck product, Cupiimine, is used for second-line treatment of rheumatoid arthritis. 

Derivative of Aspergillus terreiiS product Merck product, Zocor, has been approved for treatment of hypercholesterolemia. 

Merck Product information, liquid crystal mixtures for electro-optic displays (Merck, Darmstadt 1992)... 

The resulting yellow-brown solution is filtered, and the solid residue is washed with benzene (50 mL). The collected solution is evaporated to dryness under reduced pressure and the solid residue obtained is extracted with pentane (2 X 60 mL). The light-yellow pentane solution is filtered. (As an alternative procedure, the pentane extract is concentrated and chromatographed with pentane on an alumina column, 1 X 20 cm, Merck product, activity II-III.) Reduction of the volume of the solvent, under vacuum, to about 5 mLand cooling to -78 give light-yellow crystals of Ru(C H )(C H8). The yield is 0.225 g (70% based on RuCls 3H2O). Mp, 118-119 . 

LDPE (Petilen type F.2-12, with melt flow index of 2.0g/10 min and density of 920 kg/m ), PVC (Petvinyl type S 23/29 with K value of 54-58 in cyclohexanone at 25EC and relative viscosity of 1.354-1.417 in the same solvent), vinyl chloride monomer (VCM) and an oligomeric copolymer of vinyl chloride and polyethylene (VCO with 30% Cl) were products of Petkim-Petrochem. Ind. Inc., Turkey. The latter was a side product of VCM, and its characteristics were not disclosed. Carbon tetrachloride used in this study was a reagent grade Merck product. 

Figure 11.38 Merck production plant for Crignard-based enolate formation. Source Courtesy of Springer [96].

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