3- Mercaptopropyl-trimethoxysilane

B. Zeng and F. Fluang, Electrochemical behavior and determination of fluphenazine at multi-walled carbon nanotubes/(3-mercaptopropyl)trimethoxysilane bilayer modified gold electrodes. Talanta 64, 380-386 (2004). 

The KG-60 silica (5g) was treated with 3-mercaptopropyl trimethoxysilane (45 mmol, 8.5 mL) in dry toluene (75 mL) at reflux for 24 h. After coohng the mixture was filtered on Buchner funnel and the solid washed with Soxhlet apparatus for 16 h with a mixture of dichloromethane/diethyl ether (50 mL, 1/1 v/v). 

Immuno-polymerase chain reaction detects the presence of an antigen by PCR amplification of a single-stranded DNA bound (directly or indirectly) to an antibody Dissociation constant (3-Mercaptopropyl)-trimethoxysilane N-Hydroxysuccinimide... 

Fig. 7.2. Functionalization of a silica surface using 3-mercaptopropyl trimethoxysilane (MTS) and the bifunctional agent JV-(g-maleimidobutyryloxy)-succinimide ester (GMBS) and immobilization of biomolecules (BM).

Synthesized probe DNA was immobilized on the interior surface of silica capillary tubes using the method of Kumar [17]. The silanized probe, obtained by reacting (3-mercaptopropyl) trimethoxysilane with a 5 -thiol-labeled oligonucleotide probe... 

A similar interchain reaction takes place during hydrolysis of the monolayers of (3-mercaptopropyl)trimethoxysilane, HS(CH2)3Si(OMe)3. Although vibrational spectroscopy shows the existence of a small number of Si—OH groups on the surface after hydrolysis, the film is highly cross-linked via formation of Si—O—Si bonds with adjacent siloxane groups in the monolayer. The authors estimate that only ca 3-4% of the initial surface Si—O—CH3 groups produced Si—OH bonds after hydrolysis340. 

Coupling of zeolite crystals to SAW devices using 3-mercaptopropyl-trimethoxysilane Organic vapors [11]... 

CAS 4420-74-0 EINECS/ELINCS 224-588-5 Synonyms (3-Mercaptopropyl) trimethoxysilane Y-Mercaptopropyltrimeth-oxysilane 1-Propanethiol, 3-(trimethoxysilyl)- Silane, 3-mercaptopro-pyltrimethoxy- Trimethoxysilylpropanethiol 3-Trimethoxysilyl-1-propanethiol Empirical CsHkOsSSI... 

Figure 3.8 The most frequently used methods to immobilize capture molecules onto microarray surfaces. (A) Antibody adsorption by poly-L-lysine-, nitrocellulose-, or polyvinylidene fluoride-treated surface. (B) Covalent binding using various silane reagents of APTES (3-aminopropyl)triethoxysilane, GPTS (3-gly-cidoxypropyl)trimethoxysilane, and MPTS (3-mercaptopropyl)trimethoxysilane. (C) Affinity interactions by biotin/streptavidine or histidine-tag/nickel-nitrilotri-acetic acid. (D) Diffusion-based (hydrogel) antibody-immobilization technique.

Mercaptopropyl) trimethoxysilane y-Mercaptopropyltrimethoxysilane. See Mercaptopropyltrimethoxysilane 2-Mercaptopyridine-N-oxide, sodium salt. See Sodium pyrithione... 

Plasma treatment of microchannels can be useful for improving the functionality of microdevices. For example, previous studies have shown that PDMS microchannels can be made hydrophilic by the addition of silane molecules with polar head groups [6]. In this process (3-mercaptopropyl)trimethoxysilane (3-MPS) was absorbed to PDMS to increase the hydrophilic properties of microchannels. Additionally, plasma polymerization has been used to induce in the long-term hydrophilic surface modification by covalently bonding a polymer layer to the surface. Barbier et al. [7] describe a method based on plasma polymerization modification with acrylic acid coatings. First, argon plasma pretreatment was used to activate trace oxygen molecules in the chamber, which partially oxidize the top layer of the substrate. This step cross-linked the surface to reduce ablation of silicon... 

Mercaptopropyl-trimethoxysilane (MPS) Inhibition studied by IRRAS as function of MPS pretreatment concentration in ethanol 1060... 

C. A. Goss, D. H. Charych, M. Majda Application of (3-Mercaptopropyl)trimethoxysilane as a Molecular Adhesive in the Fabrication of Vapor-Deposited Gold Electrodes on Glass Substrates , Ana/. Chem. 1991,63(1), 85-88. 

In this entry, several kinds of comb-shaped polymers with highly ordered side chains have been introduced as attractive organic phases for RP-HPLC. Poly(octadecyl acrylate), ODA , is one of the simplest comb-shaped polymers, and its grafting for introduction onto silica surface is done by a one-step telomerization with 3-mercaptopropyl trimethoxysilane followed by immobilization with the terminal trimethoxysilyl group grafting-to method). The chromatographic results are summarized as follows ... 

---