Propionic acid, 2-Mercapto

Reducing the availability of GABA by blocking the synthesising enzyme GAD also promotes convulsions. This may be achieved by substrate competition (e.g. 3-mercapto propionic acid), irreversible inhibition (e.g. allylglycine) or reducing the action or availability of its co-factor pyridoxal phosphate (e.g. various hydrazides such as semi-carbazide). In fact pyridoxal phosphate deficiency has been shown to be the cause of convulsions in children. 

Semitelechelic HPMA polymers were synthesized by free radical polymerization of HPMA using 2,2 -azobis(isobutyronitrile) (AIBN) as the initiator and alkyl mercaptans as chain transfer agents. Alkyl mercaptans with different functional groups, namely, 2-mercaptoethylamine, 3-mercapto-propionic acid, 3-mercaptopropionic hydrazide, and methyl 3-mercapto-propionate, were used as the chain transfer agents ST HPMA polymers... 

To reach this target, bis-aminothiazoles, aromatic aldehydes, and 2-mercapto-propionic acid or 2-mercaptosuccinic acid were adsorbed on the neutral alumina support and were microwave-irradiated under solvent-free conditions (Scheme 56). The authors reported the high level of the reaction conversion, which gave the desired products 119 in excellent yields for a rather short time (up to 7 min). 

The iodinated precursor of FTP can be prepared in a one-step synthesis from 1,12-diiodododecane and 3-mercapto-propionic acid methyl ester. The... 

A synthesis of the functional core of the antibiotic leinamycin consisted of several steps, one of them being the preparation of an alkyl-substituted thietanone in moderate yield by cyclization of 2-mercapto propionic acid derivatives in isobutyl chloroformate and in the presence of triethylamine (Scheme 20) <2003T833, 2003PS1163>. 

Fig. 5. (Left) SEIRAS of NaHA and DNA on PAMAM dendrimer SAMs after adsorption for 30 min from aqueous solutions. Dendrimer SAMs were prepared by the amide bond formation of dendrimers with active ester groups of 3-mercapto-propionic acid (MPA) SAMs on CaF2 substrates. Infrared absorption spectra of NaHA, DNA, and PAMAM dendrimer are also included. (Right) Schematic illustration of the interactions between polyelectrolytes and dendrimer SAMs. Reprinted from Ref. [110].

Mercapto nicotinic acid nicosulfuron Mercapto propionic acid vamidothion... 

Nd, Tb, Tm (286. 287) Di(2-ethylhexyl) phosphoric acid [HDEHP] in cyclohexane none glycine 3-mercapto-propionic acid < = 2.53b oT 2.85 oT 2.35... 

L-Cysteine (Cys) (= (R)-2-Amino 3-mercapto-propionic acid (3-Mercapto-I -alanine)] (amino acid)... 

SYNS 2,2-DIBUTYLDIHYDRO-6H-l,3,2-OXATHIASTANNIN-6-ONE 2,2-DIBUTYL-l-OXA-2-STANNA-3-THIACYCLOHEXAN-6-ONE DIBUTYLTIN-0,S-MERCAPTOPROPIONATE DIBUTYLTIN-S,0-3-MERCAPTOPROPIONATE DIBUTYLTIN-S,0-p-MERCAPTOPROPIONATE DIBUTYL(3-MERCAPTO-PROPIONATO(2-))TIN MERCAPTO-PROPIONIC ACID, DIBUTYLTIN SALT... 

C. Spegel, A. Heiskanen, J. Acklid, A. Wolff, R. Taboryski, J. Emneus and T. Ruzgas, On-chip determination of dopamine exocytosis using mercapto-propionic acid mothfied microelectrodes. Electroanalysis, 19(2-3), 263-271 (2007). 

Fig. 1. (A) Unfiltered electrochemical STM image, taken in 0.1 M KCIO4 electrolyte solution, of an Au(l 11) electrode modified wiih [Os(bpy)2[4-(aminomethyl)pyridine]Cl](PF6) using 3-mercapto-propionic acid and DCC. Tip bias = -50 mV, tuimeling current =1.0 NA, scan rate 5.1 Hz. (B) Structure and proposed binding mode of the covalently immobilized osmium complex.

Mercapto-propanoic acid 3-Mercaptopropionic acid NSC 437 Propanoic acid, 3-mercapto- Propionic acid, 3-merc-apto- 3-Thiopropanoic acid 3-Thiopropionic acid P-Thiopropionic acid. 

Cysteine, (Cys, C), a-amino-jS-mercapto-propionic acid, HS-CH2-CH(NH2)-COOH, C3H7NO2S, Mr 121.16 Da, a proteinogenic amino acid. 

The redox reactions of metal proteins such as cytochrome c (cyt. c) are known to be promoted by modifying electrodes with SAMs of nitrogen-containing heterocyclic molecules. SEIRAS studies of the modified electrodes directed toward the understanding the promotion mechanism have been reported. The systems reported so far are 2-pyridinethiol, 4-pyridinethiol (4-PySH), bis(2-pyridyl)disul-fide, bis(4-pyridyl)disulfide, 2-pyrimidinethiol, 6-amino-8-purinethiol, mercapto-propionic acid, mercaptoethanol, 4,4 -dithiodipyridine, and L-cysteine [95-99]. 

Other complexing agents used to eliminate or reduce the influences of metal ions on the determination of hydride forming elements are cyanides, thiocyanates, tartaric acid, citric acid, ammonium fluoride, and 2-mercapto-propionic acid. 

M. Walti, D. B. Hope, Synthesis of [l-(L-2-hydroxy-3-mercapto-propionic acid)] oxytocin. A highly potent analog of oxytocin. J.C.S. Perkin I 1946-1950 (1972)... 

Fia. 4. Relation between the molar extinction coefficient of the nitroprusside color in water and its increase in 7 M urea for different thiols. Points from left to right are Thioglycolic acid, 8-mercapto-propionic acid (upper), homocysteine (lower) /3-mercaptoethanol (upper), cysteine (lower), coenzyme A, L-cysteinyl-n-valine, glutamyl-cysteine, L-oysteinyl-i.-valine, phenacetyl-cysteinyl-glycine, glutathione, phenacetyl-cysteinyl-D-valine. 

The enzyme is specific for thiol esters of the type of S-acetyl and S-butyryl glutathione. Besides the three thiol esters already discussed, ethyl thiol-acetate, butyl thiolacetate, acetyl thioglycolic acid, acetyl mercapto propionic acid, S-acetyl-2 mercaptoethanol, acetyl thiomalic, acetyl coenzyme A, and butjryl coenzyme A were inactive with the purified enzyme. Crude extracts of liver attacked butyl thiolacetate and acetyl coenzyme A slowly. 

C4H8O2S 3-mercapto-propionic acid methyl ester 2935-90-2 ... 

---