Membranes, Lipids, and Fatty Acids

Studies of membranes, hpids (including phospholipids), and other such amphiphilic biomolecules on electrodes are rather hmited due to the redox inactivity of these materials. Nevertheless, a few reports exist of studies of bilayer membranes and hpid amphiphiles on SERS surfaces and are mentioned here as exemplar studies due to the unique insight they offer. 

As noted above hpid bilayer films supported on electrodes represent an interesting bioelectrochemical interface where the potentials are of the same order as those of physiological systems, and can be readily modulated. Nevertheless, this area remains less studied except in the case of enzyme complexes such CcO where the hydrophobic environment of the lipids is necessary to maintain the integrity ofthe enzyme when immobilizing it on electrodes [304, 314]. Studies of the interaction of drugs with hpid membranes are important from many points of view, particularly considering the fact that nearly 50% of drug molecules have mem- 

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