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Megestrol acetate

Megestrol acetate can be recrystakhed from aqueous methanol (108). It is soluble in acetone, chloroform, and ethanol slightly soluble in ether and fixed oils and insoluble in water (107). Additional spectral and physical data have been pubHshed (62). [Pg.217]

Megestrol acetate (79) is stmcturaHy related to progesterone (1). It has been prepared from medroxyprogesterone acetate (74) by chloranil-mediated dehydrogenation. It also has been prepared from hydroxyprogesterone acetate (42) via 6-methylenation and double-bond migration (109,110). [Pg.217]

Noncontraceptive Uses of Progestins. Progestins have other therapeutic uses aside from contraception. Hormone-dependent tumors and cysts involving reproductive tissues respond to progestins. Megestrol acetate and MPA are the two most commonly used progestins to treat breast cancer... [Pg.223]

In addition to the sex hormones and corticosteroids, other steroid dmgs have substantial worldwide markets. For example, cytostatic hormones had worldwide sales of approximately 1.8 biUion in 1994. Included in these 1.8 biUion are several steroids or steroid-mimetics such as megestrol acetate and tamoxifen (282), respectively (262). [Pg.448]

Medroxyprogesterone Acetate Megestrol Acetate Melengestrol Acetate Norethindrone Pregnenolone Acetate Progesterone... [Pg.445]

Acetoxolone aluminum salt Aluminum amalgam Dinoprostone Aluminum tert-butoxide Megestrol acetate Aluminum chloride Acebutolol... [Pg.1611]

Mepenzolate bromide Pipenzolate bromide Pipoxolan HCI Benzoic anhydride Flavoxate HCI Benzonitrile Fentiazac Benzophenone Diphenidol Phenytoin 1,4-Benzoaquinone Dobesilate calcium Ethamsylate Megestrol acetate Benzotetronic acid... [Pg.1615]

Mindiab - Glipizide Minias - Lormetazepam Minibetic - Glipizide Minigest - Megestrol acetate Minihep - Heparin... [Pg.1718]

Megestrol acetate—has glucocorticoid-like activity ° Mifepristone (RU 486)—antagonizes glucocorticoid receptors... [Pg.687]

Other drugs with glucocorticoid activity (e.g., megestrol acetate, medroxyprogesterone)... [Pg.693]

Progestins Megestrol acetate Med roxyp rogestero ne 40 mg orally four times daily 400-1000 mg IM every week Weight gain, hot flashes, vaginal bleeding, edema, thromboembolism... [Pg.1317]

Antiandrogens inhibit the formation of the DHT-receptor complex and thereby interfere with androgen-mediated action at the cellular level.22 Megestrol acetate, a progestational agent, also is available and has antiandrogen actions.21 Finally, the conversion of testosterone to DHT may be inhibited by 5-a-reductase inhibitors.6... [Pg.1362]

Fluoxetine Megestrol acetate 20 mg 20-40 mg Once daily Once daily... [Pg.362]

Prazosin (Minipress) Alfuzosin (Uroxatral) Terazosin (Hytrin) Doxazosin (Cardura) Tamsulosin (Flomax) Finasteride (Proscar) Dutasteride (Avodart) Bicalutamide (Casodex) Flutamide (Eulexin) Leuprolide (Lupron) Nafarelin (Synarel) Megestrol acetate... [Pg.946]

See other pages where Megestrol acetate is mentioned: [Pg.600]    [Pg.600]    [Pg.600]    [Pg.211]    [Pg.212]    [Pg.444]    [Pg.405]    [Pg.443]    [Pg.443]    [Pg.117]    [Pg.444]    [Pg.921]    [Pg.921]    [Pg.1610]    [Pg.1716]    [Pg.1716]    [Pg.1722]    [Pg.1755]    [Pg.213]    [Pg.546]    [Pg.587]    [Pg.1232]    [Pg.1232]    [Pg.2280]    [Pg.2398]    [Pg.2405]    [Pg.1296]    [Pg.1318]    [Pg.1362]    [Pg.149]    [Pg.220]    [Pg.835]    [Pg.312]   
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