Medicago truncatula

M. J. Harrison and R. A. Dixon, Isoflavonoids accumulation and expression of defense gene transcripts during the establi.shment of vesicular-arbuscular mycorrhizal associations in roots of Medicago truncatula. Mol. Plant-Microbe Interact. 6 ... 

H. Liu, A. T. Trieu, L. A. Blaylock, and M. J. Harrison, Cloning and characterization of two phosphate transporters from Medicago truncatula roots Regulation in response to phosphate and to colonization by arbuscular mycorrhizal fungi. Mol. Plant-Microbe Interact. 11 A (1998). 

Lohse, S., W. Schliemann et al. (2005). Organization and metabolism of plastids and mitochondria in arbuscu-lar mycorrhizal roots of Medicago truncatula. Plant Physiol. 139(1) 329-340. 

COOK, D.R., Medicago truncatula - a model in the making , Curr. Opin. Plant Biol., 1999, 2, 301-304. 

HUHMAN, D.V., SUMNER, L.W., Metabolioc profiling of saponins in Medicago sativa and Medicago truncatula using HPLC coupled to an electrospray ion-trap mass spectometer, Phytochemistry, in press. 

SUZUKI, S., ACHNINE, L., HUHMAN, D., SUMNER, L.W., DIXON, R.A., A functional genomics approach to the triterpene saponin biosynthetic pathway in Medicago truncatula, Phytochemical Society of North America, 2001, Oklahoma City, OK... 

Figure 11.1 A schematic overview of the Noble Foundation Medicago truncatula functional genomics program.

Shao, H., He, X., Achnine, L., Blount, J.W., Dixon, R.A. and Wang, X., Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula. The Plant Cell, 2005, 17, 3141-3154. 

Naoumkina MA, He XZ, Dixon RA (2008) Ehcitor-induced transcription factors for metabolic reprogramming of secondary metabolism in Medicago truncatula. BMC Plant Biol 8 132... 

Kloot and Boyce (21) 1982 Polygonum aviculare Medicago truncatula ... 

Some species contain a closely related enzyme activity to DFR that can act on tlavanones, termed the flavanone 4-reductase (FNR), which may represent a variant DFR form. This is discussed in more detail in Section 3.4.7. 5-Deoxyleucoanthocyanidin compounds are known to occur in legumes, and analysis of two recombinant DFR proteins (MtDFRl and MtDFR2) from Medicago truncatula (barrel medic) has found activity on the 5-deoxyDHF substrates fustin and dihydrorobinetin. Indeed, fustin was the preferred substrate of both recombinant enzymes. MtDFRl and MtDFR2 showed distinct enzyme characteristics, and overexpression of MtDFRl but not MtDFR2 promoted anthocyanin biosynthesis in flowers of N. tabacum. 

Xie, D.-Y. et al., Molecular and biochemical analysis of two cDNA clones encoding dihydro-flavonol-4-reductase from Medicago truncatula. Plant Physiol., 134, 1, 2004. 

Xie, D.-Y., Sharma, S.B., and Dixon, R.A., Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana. Arch. Biochem. Biophys., 422, 91, 2004. 

Liu, C.J. et al., Regiospecific hydroxylation of isoflavones by cytochrome P450 81E enzymes from Medicago truncatula. Plant J., 36, 471, 2003. 

Pang Y, Peel G, Wright E, Wang Z, Dixon RA. 2007. Early steps in proanthocyanidin biosynthesis in the model legume Medicago truncatula. Plant Physiol 145 601-615. 

Farag MA, Huhman DV, Dixon RA, Sumner LW. 2008. Metabolomics reveals novel pathways and differential mechanistic and elicitor-specific responses in phenylpropanoid and isoflavonoid biosynthesis in Medicago truncatula cell cultures. Plant Physiol 146 387 402. 

Gonzalez-Rizzo S, Crespi M, Frugier F. 2006. The Medicago truncatula CRE1 cytokinin receptor regulates lateral root development and early symbiotic interaction with Sinorhizobium meliloti. Plant Cell 18 2680-2693. 

Naoumkina M, Farag MA, Summer LW, Tang Y, Liu C-J, Dixon RA. 2007. Different mechanism for phytoalexins induction by pathogen and wound signals in Medicago truncatula. Proc Natl Acad Sci USA 104 17909-17915. 

Pang Y, Peel GJ, Sharma SB, Tang Y, Wang Z, Dixon RA. 2008. A transcript profiling approach reveals an epicatechin-specific glucosyltransferase expressed in the seed coat of Medicago truncatula. Proc Natl Acad Sci USA 105 14210-14215. 

Wasson AP, Pellerone FI, Mathesius U. 2006. Silencing the flavonoid pathway in Medicago truncatula inhibits root nodule formation and prevents auxin transport regulation by rhizobia. Plant Cell 18 1617-1629. 

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