Measles virus encephalitis

Japanese encephalitis virus envelop protein yes measles virus H and F protein yes... 

Using RNA-templated sequencing, vaccine-strain measles virus has been implicated as the cause of death in three immunocompromised children with inclusion body encephalitis (6). The authors referred to a case of measles vaccine virus-associated giant cell pneumonia in a patient with advanced HIV infection. 

Subacute sclerosing panencephalitis and milder encephalitis are caused by measles virus. Focal lymphocytic inflammation in the leptomeninges and perivascular spaces, with many CD4-positive cells, patchy GFAP-positive fibrillary astrocytosis, and occasional microglial nodules, involves the cerebral cortex. Diffuse mononuclear inflammation, gliosis, and loss of myelin occur in subcortical white matter. Inclusion bodies are Cowdry type A and may be seen on H E-stained slides their specific identification requires IHC. °... 

Measles is a severe, highly contagious, acute infection that frequently occurs in epidemic form. After multiplication within the respiratory tract the virus is transported throughout the body, particularly to the skin where a characteristic maculopapular rash develops. Complications ofthe disease can occur, particularly in malnourished children, the most serious being measles encephalitis which can cause permanent neurological injury and death. 

III. Vaccines containing measles, mumps, and rubella viruses in any combination (for example MMR, MR, M, R) A. Anaphylaxis or anaphylactic shock B. Encephalopathy (or encephalitis) C. Any acute complication or sequel (including death) of the above events 0-4 hours 5-15 days Not applicable... 

Measles, mumps, or rubella virus Anaphylaxis or anaphylactic shock within 4 hours encephalopathy or encephalitis within 5-15 days (not less than 5 days, not more than 15 days)... 

Wild, T.F., Bernard, A., Spehner, D., Villeval, D., and Drillien, R. 1993. Vaccination of mice against canine distemper virus-induced encephalitis with vaccinia virus recombinants encoding measles or canine distemper vims antigens. Vaccine 11, 438-444. 

The molecular weight of nucleic acids, in various types of virus, varies from 2 to 160 million. RNA and the much larger DNA types are about equally common in viruses infecting Man. Typical DNA viruses are the adenoviruses (causing infections of the respiratory tract), the poxviruses, and the herpesviruses. Typical RNA viruses are the myxoviruses (including influenza), paramyxoviruses (mumps and measles), and those causing yellow fever and encephalitis. The nucleic acids are double-stranded in some types, but single-stranded in others. 

Rammohan KW, McFarland HF, McFarlin DE. Induction of subacute murine measles encephalitis by monoclonal antibody to virus haemagglutinin. Nature 1981 290(5807) 588-589... 

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