Mathis studies

Ederle and Mathis, in a very careful study, recently showed by SEC with combined mass and molecular weight (light scattering) detectors that exactly six polystyryllithium chains can be coupled with pure fullerene (C60) in toluene. Furthermore, comparison of the mass and UV (set at 320 nm sensitive to the presence of C60) traces proved the uniformity of the C60 core in the star polymer [49],... 

F.-X. Mathy, C. Lombry, R. Verbeeck, and V. Preat. Study of percutaneous penetration of flubiprofen by cutaneous and subcutaneous microdialysis after iontophoretic delivery in rat. J. Pharm. Sci. 94 144—152 (2005). 

Wilder P, Mathys K, Brenneisen R, Kalix P, Fisch HU. (1994). Pharmacodynamics and pharmacokinetics of khat a controlled study. Clin Pharmacol Ther. 55 556-62. 

Dennis J. McKenna, Adil J. Nazarali, Andrew J. Hoffman, David E. Nichols, C. A. Mathis, and Juan M. Saavedra. "Common receptors for hallucinogens in rat brain a comparative autora-diographic study using [125IJLSD and [125IJ-DOI, a new psychotomimetic radioligand." Brain Research 476 (1989) 45-56. 

Dennis J. McKenna, C. A. Mathis, A. T. Shulgin, and J. M. Saavedra. "Hallucinogens bind to common receptors in the rat fore-brain a comparative study using 125I-LSD and... 

Deplazes, P., Dinkel, A. and Mathis, A. (2003) Molecular tools for studies on the transmission biology of Echinococcus multilocularis. Parasitology 1 27, S53-61. 

Following this study, Korovin and coworkers tested cryptands 23b-f which are used in time-resolved luminescent immunoassays (Mathis, 1993) for the sensitization of Ybm luminescence (Korovin et al., 2002b). From the lifetimes determined in both water and deuterated water, one calculates that the hydration number varies from 2 (23b), to 1.5 (23a, 23e), and finally to 1 (23c, 23d, 23f). Quantum yields were not determined, but luminescence intensities relative to the cryptate with 23a (in water, at room temperature) point to cryptands 23c and 23d being the best sensitizers of the Yb111 luminescence with a seven-fold enhancement, while cryptates with 23e and 23b are only 1.5- to 1.8-times more luminescent. 

The bioconcentration of chemicals in plants, especially plants that are important links in the food chain, is of evident concern. Chemicals may be taken up in aqueous solution via roots or leaves (the latter particularly if chemicals are present in rainfall), or absorbed directly from the atmosphere via leaves if they are in the vapor phase. However, in contrast to the large number of QSAR studies on bioconcentration in aquatic species, there have been relatively few QSAR investigations of bioconcentration by plants. Several mechanistic models have been propounded (e.g., Paterson et al., 1994, Trapp and Mathies, 1995 Hung and Mackay, 1997). 

In a previous study we have found that, at low temperature, PS-I electron transfer is largely blocked away from A, and that the state (P-700+, A, ) decays with a half-time of 130us. Analysis of the absorption spectrum of that state showed that A, is presumably a quinone radical anion (Brettel et al, 1986). Chemical analysis, following separation by HPLC, has shown that phylloquinone (a naphthoquinone also named vitamin Kj) is the only quinone present in PS-I. We have found 2 moles of phylloquinone per PS-I. Extraction with dry hexane does not change the electron transfer reactions this treatment only extracts only one phylloquinone per PS-I (Biggins and Mathis, 1987). 

Ikegami, I., Setif, P. and Mathis, P. 1987. Absorption studies of Photosystem I photochemistry in the absence of vitamin Kj. Biochim. Biophys. Acta (in press). 

Mathis, P., Ikegami, I. and Setif, P. 1987. Nanosecond flash studies of the absorption spectrum of the Photosystem I primary acceptor A0 (submitted). 

Bohnen NI, Kaufer DI, Ivanco LS, Lopresti B, Koeppe RA, Davis JG, Mathis CA, Moore RY, DeKosky ST (2003) Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease an in vivo positron emission tomographic study. Arch Neurol 60 1745-1748... 

Dolence, J.M., Cassidy, P.B., and Mathis, J.R. (1995). Yeast protein farnesyltransferase steady-state kinetic studies of substrate binding. Biochemistry 34 16687-16694. 

Mathis et al. have studied by low-angle X-ray diffraction the extension of a... 

Shiroff RA, Mathis J, Zehs R, Schneck DW, Babb JD, Leaman DM, Hayes AH Jr. Propranolol rebound—a retrospective study. Am J Cardiol 1978 41(4) 778-80. 

Les.), and Couceiro, de Almeida, and Freire (1953) have localized it histo-chemically in the electrical tissue of Electwphorus electricus L. The distribution of carbonic anhydrase in several tissues of two teleosts and its inhibition in vivo by the sulfonamides have been investigated by Maetz (1953a,b). The presence of cathepsin in the stomachs of various animals including pike and trout has been established by Buchs (1954). A new advance has also been made in the comparative study of pepsin. This enzyme, previously crystallized from salmon (Norris and Elam, 1940), halibut (Eriksen, 1943), and shark (Sprissler, 1942), has now been crystallized from three species of tuna (Norris and Mathies, 1953). These interesting researches have shown that fish pepsins differ in crystal structure, amino acid composition, and specificity from swine or bovine pepsins and show a closer relationship to one another. As pointed out by Velick and Udenfriend (1953), specificity requirements toward substrates are less exacting with extracellular enzymes. 

The most recent measurement was carried out by Setif and Mathis , who looked particularly for the probable cause for the variance in the redox-potential values reported in the literature. These authors used chloroplast thylakoid lamellae and simpler complexes fractionated by treatment with digitonin, Triton and other detergents or combinations thereof. A CPI complex i.e., one in which all iron-sulfur clusters were removed) prepared from tobacco by SDS fractionation was also used in their study. 

P Mathis, I Ikegami and P S0tif (1988) Nanosecond fiash studies of the absorption spectrum of the photosystem I primary acceptorPhotosynthesis Res 16 203-210... 

For their kinetic studies, Mathis and Setif " used enriched PS-I particles with Chl/P700=65 110,... 

Fig. 9. (A) Absorbance changes produced by enriched PS l-p" particles prepared from spinach and under mildly reducing condition and excited with 30-ps, 532-nm flashes (note that sample concentrations and number of flashes used for averaging the signals were not the same) (B) absorbance changes in the PS 1-110 particles containing dithionite. Figure source Mathis and S6tif (1988) Kinetic studies on the functbn ofA in the photosystem I reaction center. FEBS Lett 237 66,67.

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