Thyroid hormones, maternal

The transplacental passage of maternal iodothyronines is quantitatively modest, although it might be sufficient to ensure adequate fetal development. Maternal thyroid hormone secretion is markedly increased during pregnancy (by 25-50%) thyroid therapy should therefore be carefully adjusted during pregnancy (58). [Pg.350]

Trimester-Specific Changes in Maternal Thyroid Hormones Implications for Iodine Nutrition... [Pg.403]

Although for years it has been published that the human fetus develops in the absence of thyroid hormones, there is increasing evidence of the active transfer of maternal thyroid hormones from the mother to the human fetus. [Pg.618]

ADHD in iodine-deficient children could be due to an inadequate supply of maternal thyroid hormone... [Pg.661]

Altogether, these findings indicate not only that a transfer of maternal thyroid hormone, namely of T4, to the fetus is effective from early pregnancy, but also that the systems regulating the availability of T3 to the fetal brain are expressed and likely operating by that time. [Pg.680]

During pregnancy and breast-feeding, both fetus and neonate are dependent on maternal thyroid hormones, of which iodine is an essential component. Thyroid hormones regulate key biochemical reactions, are essential for... [Pg.1135]

Maternal thyroid hormone aberration during pregnancy r resents an identifiable cause of cerebral palsy (12) and Icwered IQ (10) in children ... [Pg.59]

Work performed by Weiss and Novak 5 and by Sweney and Shapiroi strongly suggested the possibility that maternal thyroid hormones are available to the rat embryo before onset of fetal thyroid function, despite opinions to the contrary 1 . We decided to re-investigate this possibility by measuring T4 and T3 concentrations in embryonic and fetal tissues. We had developed specific and sensitive RIAs 18, and extensive extraction and purification... [Pg.188]

Morreale de Escobar G, Obregdn MJ, Escobar del Rey F, Fetal and maternal thyroid hormones. Horm Res 26 12 (1987)... [Pg.200]

P.O.D. Pharoah, K.J. Connolly, R.P. Ekins and A.G. Harding, Maternal thyroid hormone levels in pregnancy and the subsequent cognitive and motor performance of the children, Clin. Endocrinol. 21 265-270 (1984). [Pg.228]

R.P. Ekins, A.K. Sinha and R.J. Woods, Maternal thyroid hormones and development of the foetal brain, 3 Iodine nutrition, thyroxine and brain development", N. Kochupillai, M.G. Karmakar and V. Ramalingswami eds., Tata McGraw-Hill Publ., New Dehli (1986), pp. 222-245. [Pg.229]

R.P. Ekins, A.K. Sinha, R.J. Woods, Maternal thyroid hormones and development... [Pg.330]

R. Ekins, Role of serum thyroxine-binding proteins and maternal thyroid hormones in... [Pg.331]

Ekins, R. P. Hypothesis The roles of serum thyroxine binding proteins and maternal thyroid hormones in foetal development. Lancet (i) 1129-1132, 1985... [Pg.373]

FETO-MATERNAL THYROID HORMONE RELATIONSHIPS IN IODINE DEFICIENCY AN EXPERIMENTAL APPROACH... [Pg.171]

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