Mass spectrometry forensic toxicology

Cheze M, Duffort G, Deveaux M, Pepin G. Hair analysis by liquid chromatography-tandem mass spectrometry in toxicological investigation of drug-facilitated crimes report of 128 cases over the period June 2003—May 2004 in metropolitan Paris. Forensic Sci Int 2005 153 3-10. 

P. Marquet. Progress of Liquid Chromatography-Mass Spectrometry in Clinical and Forensic Toxicology, Therapeutic Drug Monitoring, 24, no. 2, (2002). 

Gas chromatography-mass spectrometry (gc/ms GC-MS), 4 616 6 381, 431 archaeological materials, 5 743 use in forensic toxicology, 12 91 Gas-controlled heat pipe, 73 234—235 Gas cracking furnaces, additives to, 10 609-610 Gas diffusion... 

Maurer HH. 2002. Role of gas chromatography-mass spectrometry with negative ion chemical ionization in clinical and forensic toxicology, doping control, and biomonitoring. Ther Drug Monit 24 247. 

Maurer, H. H. (2007). Current role of liquid chromatography-mass spectrometry in clinical and forensic toxicology. Anal. Bioanal. Chem. 388 1315-1325. 

Peters FT (2011) Recent advances of liquid chromatography-(tandem) mass spectrometry in clinical and forensic toxicology. Clin Biochem 44 54-65... 

Mass spectrometry (MS) is playing an increasingly visible role in the molecular characterization of combinatorial libraries, natural products, drug metabolism and pharmacokinetics, toxicology and forensic investigations, and proteomics. Toward this end, electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), and atmospheric pressure photo-ionization (APPI) have proven valuable for both qualitative and quantitative screening of small molecules (e.g., pharmaceutical products) [9-14]. 

Fenton J, Schaffer M, Chen NW, Bermes EW Jr. A comparison of enzyme immunoassay and gas chro-matography/mass spectrometry in forensic toxicology. J Forensic Sci 1980 25 314-9. 

Cairns T, Kippenberger DJ, Scholtz H, Baumgartner WA (1995) determination of carboxy-THC in hair by mass spectrometry/mass spectrometry. In de Zeeuw RA, Al Hosani I, Al Munthiri S, Maqbool A (eds) Hair Analysis in Forensic Toxicology proceedings of the 1995 international conference and workshop. The Organizing Committee of the conference, Abu Dhabi, pp 185-193... 

Electron-molecule reactions This process is also referred to as electron capture detection mass spectrometry (ECD-MS), and is amenable to compounds containing electrophilic moieties (such as compounds with positive electron affinities). ECD-MS has been investigated and used extensively for analyses of many classes of environmental contaminants and for forensic toxicological applications. 

Maurer HH. Multi-analyte procedures for screening for and quantification of drugs in blood, plasma, or serum by liquid chromatography single stage or tandem mass spectrometry (LC-MS or LC MS/MS) relevant to clinical and forensic toxicology. Clin Biochem 2005 38 310-318. 

Van Bocxlaer JF, Clauwaert KM, Lambert WE, et al. (2000) Liquid chromatography-mass spectrometry in forensic toxicology. Mass Spectrometry Review 19(4) 165-214. 

The application of GC to steroid analysis seems to face many difficulties owing to the insufficient volatility and thermolability of the steroids. The development of high-resolution gas chromatography (HRGC) and various derivatization procedures enables the efficient separation of complex steroid mixmres for application in clinical- and forensic toxicology and natural product analysis. The development of low-cost mass spectrometry (MS)... 

Indeed, mass spectrometry is the method of choice for an amazing range of applications, from structure determination of proteins to forensic toxicology, from fundamental studies of reaction kinetics to imaging tissues. And that breadth of use and dominance of mass spectrometry is well represented in the chapters assembled here. 

James, Stuart H., and Jon J. Nordby, eds. Forensic Sdence An Introduction to the Scientific and Investigative Techr niques. 3d ed. Boca Raton, Fla. CRG Press, 2009. Discusses mass spectrometry techniques in relation to forensic applications, including forensic toxicology, controlled substance identification, and DNAanal) is. 

A Comparison of Enzyme Immunoassay and Gas Chromatography/Mass Spectrometry in Forensic Toxicology J. Forensic Sci. 25(2) 314-319 (1980) CA 93 20145z... 

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