Mass perfluorinated compounds

The molecular ion is usually not observed in the mass spectra of aliphatic fluorinated compounds (>ethane). Common losses are F. HF, or CF3. Frequently observed ions lie at m/zs 31 (CF), 50 (CF2). and 69 (CF3). If mass 69 is intense, a CF3 group is present. The presence of a small m/z 51 peak indicates the presence of carbon, hydrogen, and fluorine. If a m/z 51 peak is intense, then CHF is present. The absence of m/z 51 and/or m/z 47 (without chlorine) suggests a perfluorinated compound. 

Llorca M, Farre M, Pico Y, Barcelo D (2011) Analysis of perfluorinated compounds in sewage sludge by pressurized solvent extraction followed by liquid chromatography-mass spectrometry. J Chromatogr A 1218(30) 4840 1846... 

Wille K, Vanden Bussche J, Noppe H, De Wulf E, Van Caeter P, Janssen CR, De Brabander HF, Vanhaecke L (2010) A validated analytical method for the determination of perfluorinated compounds in surface-, sea- and sewagewater using liquid chromatography coupled to time-of-flight mass spectrometry. J Chromatogr A 1217(43) 6616-6622... 

Keywords Dietary intake, Food analysis, Liquid chromatography, Mass spectrometry, Perfluorinated compounds, Perfluorinated compounds, Risk assessment... 

Zhao, X., Li, J., Shi, Y, Cai, Y, Mou, S., and Jiang G. 2007. Determination of perfluorinated compounds in wastewater and river water samples by mixed hemimicelle-based solid-phase extraction before liquid chromatography-electrospray tandem mass spectrometry detection. J. Chromatogr. A 1154 52-59. 

Yang, L., Yu, W., Yan, X., and Deng, C. 2012. Decyl-perfluorinated magnetic meso-porous microspheres for extraction and analysis perfluorinated compounds in water using ultrahigh-performance liquid chromatography-mass spectrometry. J. Sep. Sci. 35 2629-2636. 

Moriwaki H. Liquid chromatographic-mass spectrometric methods for the analysis of persistent pollutants polycyclic aromatic hydrocarbons, organochlorine compounds and perfluorinated compounds. Curr Orga Chem 2005 9(9) 849—57. 

Luque N, Ballesteros-Gomez A, van Leeuwen S, Rubio S. Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chroma-tography/ion isolation-based ion-trap mass spectrometry. J Chromatogr A 2010 1217(24) 3774-82. 

Song LG, Wellman AD, Yao HF, Adcock J. Electron capture atmospheric pressure photoionization mass spectrometry analysis of fullerenes, perfluorinated compounds, and pentafluorobenzyl derivatives. Rapid Comm Mass Spec 2007 21(8) 1343—51. 

Under RP-Cis column separation conditions, no differentiation between conventional AE and fluorinated AE in retardation behaviour could be observed. The application of a perfluorinated RP-C8 column to a mixture of standards of non-ionic fluorinated surfactants and the extracts of wastewater sludges spiked with these compounds using realistic concentrations, however, resulted in good separation of AE and fluorinated AE (cf. mass traces and TIC in Fig. 2.9.46(a), (b) or (e) and Fig. 2.9.46(c), (d) or (e), respectively) or matrix and fluorinated AE surfactants (Fig. 2.9.46(f), (g) or (h), respectively) [52]. 

Fig. 2.9.46. (e) APCI-LC-MS(+) RIC of a mixture of standards containing a conventional AE blend (C12 and C14 homologues) and a fluorinated non-ionic surfactant blend (C F2 +i-(CH2-CH2-0)m-H n = 6 and 8) (a)-(d) selected mass traces of conventional C12 and C14 AE compounds or CB and Cg fluorinated AE compounds (h) APCI-LC-MS(-I-) RIC of wastewater sludge extract containing non-ionic fluorinated surfactants (f) and (g) selected mass traces of C6 and C8 fluorinated AE compounds extracted from sewage sludge. Gradient elution separated on perfluorinated RP-Cg column [52]. 

M. Kotrebai, J. F. Tyson, E. Block, P. C. Uden, High performance liquid chromatography of selenium compounds utilising perfluorinated carboxylic acid ion pairing agents and inductively coupled plasma and electrospray ionisation mass spectrometric detection, J. Chromatogr. A, 866 (2000), 51-63. 

As an initial exploratory experiment dodecafluoro n-pentane was chosen as a model compound for P.T.F.E. to simulate part of the perfluorinated molecular chain and allowed to adsorb at 0.13 pPa pressure and ambient temperature on a freshly prepared iron film produced by an evaporation process in situ from an iron wire wrapped around a tungsten filament. The events inside the vacuum chamber were followed with an MS 10 mass spectrometer and (where appropriate) a Pi rani gauge. These experiments suggest that the clean iron acts as a catalyst for the breakdown of the perf1uorinated alkane producing a variety of transiently reactive fragments, such as CF2, that in turn may react with the borosilicate (Pyrex) glass walls of the reaction chamber. 

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