Marine steroidal glycosides

The study of marine natural products has great possibilities for new products. Thus, Paul Scheuer from Hawaii studied bioactive compounds from mollusks and other marine sources. Luigi Minale, Raffaele Riccio and Maria lorizzi from Italy, conducted a comprehensive research on marine steroidal glycosides. Joel Kashman from Tel-Aviv University investigated on the biologically active natural products from marine organisms. 

Vazquez, M. J., Quinoa, E., Riguera, R., San-Martin, A., and Darias, J., Antarctic marine metabolites new polyhydroxylated steroidal glycosides from the starfish Odontaster validus, Liebigs Ann. Chem., 1257, 1993. 

The steroidal glycoside hapaioside, fn>m a marine sponge, contains a rare 6-deoxy-P-L-altropyranoside unit 15 glycosidically linked to 0-3 of a 19-norpregnane structure,whilst the new monosaccharide L-dianose (16) has been isolated from a Chinese medicinal plant ... 

Ivanchina NV, Kicha AA, Stonik VA (2011) Steroid glycosides from marine organisms. Steroids 76 425 54... 

Ali, M.S. et al. (2002) Steroid and antibacterial steroidal glycosides from marine green alga Codium iyengarii Borgesen. Nat. Prod. Lett. 16,407 13... 

Elyakov, G.B., N.I. Kalinovskaya, V.A. Stonik, and T.A. Kuznetsova Glycosides of Marine Invertebrates VI. Steroid Glycosides from Holothurian Stichopus japonicus. Comp. Biochem. Physiol. 65B, 309 (1980). 

Andersson, L., Nasir, A., Bohlin, L., and Ketme, L. (1987b) Studies of Swedish marine organisms. IX. Polyhydroxylated steroidal glycosides from the starfish Porania pulvdlus. J. Nat. Prod., 50,944—947. 

De Marino, S., Zollo, F., Minale, L., and lorizzi, M. (1995) Isolation of thirty polyhydroxysteroids and steroid glycosides from an Antarctic starfish of the genus Echinaster, in Proceedings of the 8th International Symposium on Marine Natural Products, Tenerife, Spain, P68, pp. 221-222. 

Cachet, N., Regalado, E.L, Genta-Jouve, G., Mehiri, M., Amade, P., and Thomas, O.P. (2009) Steroidal glycosides from the marine sponge Pandaros acanihifdium. Steroids, 74, 746-750. 

Okada, Y., Matsunaga, S., Van Soest, R.W.M., and Fusetani, N. (2006) Sodokosides, steroid glycosides with an isopropyl side chain, from the marine sponge Erylus placenta. J. Org. Chem., 71, 4884—4888. 

Sandler, J.S., Forsburg, S.L., and Faulkner, D.J. (2005) Bioactive steroidal glycosides from the marine sponge Erylus lendenfddi. Tetrahedron, 61, 1199-1206. 

Dasgupta, S., Pramanik, K., and Mukhopadhyay, B. (2007) Oligosaccharides through reactivity tuning convergent synthesis of the trisaccharides of the steroid glycoside sokodoside B isolated from marine sponge Erylus placenta. Tetrahedron, 63,12310-12316. 

Phytochemistry The plant contains organic acids (tartaric, citric, and malic), essential oil, diterpenoids (phytol), triterpenoids, steroids, saponins, alkaloids, choline, vitamin C, carotene, phenylcarbonic acids (rosmarinic acid), tannins, cou-marins, flavonoids, cardiac glycosides, carbohydrates and anthocyanins (cyanin and pelargonin Akopov 1990 Plant Resources of the USSR 1991). 

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