Steroid bioactive

Bioactive Steroids from Mucor plumbeus and Coprnusmicaceus... 

Bioactive Steroidal Alkaloids from Buxus hyrcana... 

The vicinal chlorohydrin group has been identified in several bioactive steroidal compounds, such as the withanolides [97]. In biological systems, hypochlorous... 

Previously included, at least in part, in the Liliaceae or Amarylli-daceae, the Agavaceac, familiar plants in arid America, are known for (heir content of steroidal saponins which have been used for conversion to bioactive steroids of medicinal importance. It is... 

Da Silva BP, De Sousa AC, Silva GM, Mendes TP, Parente JP (2002) A New Bioactive Steroidal Saponin from Agave attenuata. Z Naturforsch 57c 423... 

Saponins constitute a structurally and biologically diverse class of molecule that are widely distributed in terrestrial plant and some marine organisms. The extreme difficulties associated with the purification of closely related saponins from a natural source provides synthesis with a realistic opportunity to contribute to the availability of homogeneous saponins. One of our current effort was being directed toward the total synthesis of bioactive steroid saponins from Chinese herbs. 

Although less effective than methyl(trifluoromethyl)dioxirane (TFDO), oxyfunctionalization of unactivated methine C-Hs with dimethyldioxirane (DDO) is feasible for various substituted steroids related to the 5/)-cholane and 5a-cholestane series to give novel mono- and dihydroxylated steroids. The reactivity and site selectivity of oxyfunctionalization is affected conspicuously by the structural and steric environments of the target methine carbon atoms. This nonenzymatic procedure may be advantageously applied to selective and short-course s)mtheses of bioactive steroids. Thus, the major reaction product of methyl... 

As vinyl triflates can be easily prepared from the corresponding ketones or aldehydes, which are abundant and wildly available, the use of vinyl triflates as starting materials in total synthesis has attracted a lot of attention [27—39]. Murai s group synthesized glycinoeclepin A by palladium-catalyzed carbonylation, using vinyl triflate as the key intermediate [40, 41]. Holt and colleagues prepared bioactive steroids [42, 43], whUe McDonald s team prepared cephalosporins [44]. 

Sautour M, Mitaine-Offer AC, Lacaille-Dubois MA (2007) The Dioscorea grams a review of bioactive steroid saponins. J Nat Med 61 91-101. doi 10.1007/sll418-006-0126-3... 

Challinor VL, Parsons PG, Chap S, White EF, Blanchfield JT, Lehmann RP et al (2012) Steroidal saponins from the roots of Smilax sp. structure and bioactivity. Steroids 77 504-511. doi 10.1016/j.steroids.2012.01.009... 

Parente JP, Pereira da Silva B (2008) Bioactive steroidal saponins from Brazilian medicinal plants. Curr Trends Med Chem 5 45-57... 

Kim YC, Che QM, Gunatilaka AAL, Kingston DGI (1996) Bioactive steroidal alkaloids from Solanum umbellifemm. J Nat Prod 59 283-285... 

Wang Y, Kays SJ (2002) Sweetpotato volatile chemistry in relation to sweetpotato weevil (Cylas formicarius) behaviour. J Am Soc Horticult Sci 127 656-662 Wanyonyi AW, Chhabra SC, Mkoji G, Eilert U, Njue WM (2002) Bioactive steroidal alkaloid glycosides from Solanum aculeastrum. Phytochemistry 59 79-84 Wanyonyi AW, Tams PK, Chhabra SC (2003) A novel steroidal alkaloid from Solanum aculeastrum. Bull Chem Soc Ethiopia 17 61-66... 

Bioactive steroids from the brown alga Sargassum carpophyllum. J. Asian Nat. Prod. Res., 4, 95-101. 

Sandler, J.S., Forsburg, S.L., and Faulkner, D.J. (2005) Bioactive steroidal glycosides from the marine sponge Erylus lendenfddi. Tetrahedron, 61, 1199-1206. 

Seo, Y., Jung, J.H., Rho, J., Shin, J., and Song, J. (1995) Isolation of novel bioactive steroids from the soft coral Alcyonium gracillimum. Tetrahedron, 51, 2497-2506. 

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