Mannan biosynthesis

Figure 6.5 The tentative coupling of PolyP and mannan biosynthesis in yeast Dol-PP, dolichyl diphosphate Dol-P, dolichyl phosphate GDPMan, GDPmannose Dol-PP-Man, dolichyl diphosphate mannose (Man) , mannan, where n is the number of mannose residues.

A number of early studies on mannan biosynthesis (29> 30) were done without a clear idea of the structure of the substance and, consequently, were difficult to interpret. With the... 

Japanese Journal of Experimental Mediciney 37, 79-81 Tanner, W. (1969) A Lipid Intermediate in Mannan Biosynthesis in Yeast , Biochemical and Biophysical Research Communications, 35,144-150 Tanner, W., Babczinski, P., Marriott, M., Hasilik, A. Lehle, L. (1979) Glycosylation of Intra- and Extra-cellular Yeast Glycoproteins , Biochemical Society Transactions, 7, 329-31... 

Antalis, C., Fogel, S. and Ballou, C. E, (1973) Genetic control of yeast mannan structure. Mapping the first gene concerned with mannan biosynthesis. J. Biol. Chem. 248, 4655-4659. 

Scheme 1. — Reactions Involved in the Biosynthesis of D-Mannan from GDP-Mannose. [The acceptor lipid in the reaction, undecaprenyl phosphate, is designated as follows ]...

Scheme 3.—Biosynthesis of the Core Oligosaccharide AT-Glycosylically Linked to L-Asparagine in Yeast Mannans.10 11 86 11 111-117-1 8-160-161...

The putative pathway of coordination of mannan and PolyP biosynthesis by cell-wall formation has been proposed (Kulaev, 1994), which explains the presence of PolyP outside of the cytoplasmic membrane (Figure 7.4). Dolichyl-phosphates (Dol-Ps) act as transmembrane carriers of carbohydrate residues in glycoprotein biosynthesis. GDP-mannose at the... 

Figure 7.4 The putative pathway of coordination of mannan and PolyP biosynthesis in yeast.

Yu. A. Shabalin, V. M. Vagabov and I. S. Kulaev (1979). On the coupling mechanism of biosynthesis of high-molecular polyphosphates and mannan in Saccharomyces carlsbergensis yeast. Dokl. Akad. Nauk SSSR, 249, 243-246. 

In Volume 33 of this Series, we presented1 a review of the crystalline structures of polysaccharides published during the period 1967-1974. Detailed accounts of progress in structural studies on specific types of polysaccharides were presented in the Proceedings of the Twenty-sixth Symposium of the Colston Research Society and were subsequently published as a book.2 Precise methods for X-ray diffraction analysis of biopolymer structures were discussed by Hukins.3 The aspects of the structures of cellulose, mannan, and xylan, their organization in the cell wall, and the biosynthesis of cell-wall polysaccharides were described by Mackie.4 Work on the structures of the connective-tissue polysaccharides, O-acetylcellulose, and the various forms of amylose was reviewed by Atkins,5 Chanzy,6 and Sarko,7... 

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