Malignant lymphoma, risk from exposure

The hypothesis that phenoxy herbicides are a cause of soft tissue sarcoma (STS) also commenced in Sweden. Three case-control studies conducted by the same investigators reported relative risks of 3.3 to 5.7 for such an association (Table V) (42-44 ). However, as with malignant lymphoma, it is difficult to explain such dramatic risks associated with short term exposures. Moreover, Wiklund and Holm (45) found no overall risk increase from STS among Swedish agriculture and forestry workers (RR—0.9 95% Cl 0.8-1.0). 

Tumorigenidty In 1193 male platers, 626 of whom had been exposed to chromium and who were followed for 27 years, mortality from lung cancer was increased in those who had been exposed (SMR = 1.46 95% Cl=0.98, 2.0) [46. Those who had been exposed also had increased mortality risks for brain tumors (SMR = 9.1 95% Cl = 1.8, 22) and malignant lymphoma (SMR=2.8 95% CI=1.05,5.5). There were higher risks of lung cancer and malignant lymphoma among those with initial chromium exposure before 1970. 

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