Male reproductive physiology

Increase basic knowledge of the mechanisms of male reproductive physiology to a level comparable to the current level of knowledge on mechanisms of female reproductive physiology. 

Modaresi, M., Mesripour, M., and Ali, R.R. 2009. The effect of cinnamon (bark) extract on male reproductive physiology in mice. Spring, 14 61-11. 

Reproductive System. The primary PGs are intimately involved in reproductive physiology (67). PGE2 and PGP2Q, are potent contractors of the pregnant utems and intravenous infusion of either of these compounds to pregnant humans produces a dose-dependent increase in frequency and force of uterine contraction. PGI2 and TXA2 have mild relaxant and stimulatory effects, respectively, on uterine tissue. The primary PGs also play a role in parturition, ovulation, luteolysis, and lactation and have been impHcated in male infertility. 

Finally, a new class of antispermatogenic agents containing the same fundamental structure cited above has been described (76JMC778). 1-Halobenzyl-l J/-indazole-3-carboxylic acids are potentially useful for birth control, and because they act after a single administration they are of interest for the physiological study of the male reproductive system. 

Identify the structures of the male reproductive system and describe the physiology of a penile erection. 

The authors concluded that the mixture induced effects on the liver and the kidney, and on the general metabolism at high doses but caused only minor effects on immune function, reproductive hormone levels, or general indices of reproductive function measures. The results suggested that additive or synergistic effects of exposure to contaminants resulting in residue levels representative of contemporary human tissue levels are unlikely to result in adverse effects on immune function or reproductive physiology in male rats. 

Griffin JE. Male reproductive function. In Griffin JE and Ojeda SR (eds.). Textbook of Endocrine Physiology. New York Oxford University, 1992 169-188. 

Lamb JC, Foster PMB. eds. Physiology and Toxicology of the Male Reproductive System. London Academic Press, 1988. 

This chapter discusses both male and female reproductive toxicity and provides an overview of reproductive physiology. 

Vol. V Male Reproductive System. Washington, D.C. American Physiological Society, 1975. 

Setchell, B.P., and G.M.H. Waites. The blood-testis barrier, pp. 143-172. In R.O. Greep and E.B. Astwood, Eds. Handbook of Physiology. Section 7 Endocrinology. Vol. V Male Reproductive System. Washington, D.C. American Physiological Society, 1975. 

Lamb, J.C., IV. 1988. Fundamentals of male reproductive toxicity testing. Pp. 137-153 in Physiology and Toxicology of Male Reproduction, J.C. Lamb, IV, and P.M.D. Foster, eds. New York Academic Press. 

Figure 3 Diagrammatic representation of a portion of a seminiferous tubule. L, Leydig cell M, myoepithelial peritubular cell SC, Sertoli cell Sg, spermatogonium Sp, spermatocyte Sd, spermatid. (Reproduced from Lamb JC, IV and Foster PMD (1988) Physiology and Toxicology of Male Reproduction. San Diego Academic Press, with permission from Elsevier.)...

Eamb JC IV and Poster PMD (eds.) (1988) Physiology and Toxicology of Male Reproduction. San Diego, CA Academic Press. 

Gray EE, Laskey JW. 1980. Mulhvariate analysis of the effects of manganese on the reproductive physiology and behavior of the male house mouse. J Toxicol Environ Health 6 861-867. 

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