Lactose maldigestion

Johnson AO, Semenya JG, Buchowski MS, et al. Correlation of lactose maldigestion, lactose intolerance, and milk intolerance. Am / Clin Nutr 57 399-401,1993a. 

The gastrointestinal manifestations of primary hereditary delayed-onset hypolactasia, while uncomfortable, are not life threatening and can be completely eliminated by dietary manipulation. Is lactose intolerance a serious health issue or just a nuisance In certain circumstances, specifically at the extremes of life (infancy and old age) lactose maldigestion may have grave health consequences. 

Lactose intolerance can be readily managed by ensuring that the amount of lactose ingested is restricted to the amount the individual can tolerate, which is related to the individual s level of residual intestinal lactase activity. Lactose maldigesters can determine their individual threshold for the occurrence of lactose intoler-... 

If specific treatment is considered necessary, supplemental lactase can be provided as replacement therapy. This is derived from specific species of yeast or fungus and is available as caplets, tablets, and drops. Whole milk pretreated with lactase is marketed in some states as Lactaid and can be used by lactose maldigesters. The availability of the replacement enzyme has made unnecessary the use of the lactose-free diet, which can be nutritionally unsound, as discussed. Also, since lactose is common in many foods and drinks and is used in... 

Carrocio A, Montalto G, Cavera G, et al. Lactose intolerance and self-reported milk intolerance relationship with lactose maldigestion and nutrient intake. /Am CollNutr 17 631-636,1998. 

Hertzler SR, Clancy SM Kefir improves lactose digestion and tolerance in adults with lactose maldigestion. J Am Diet Assoc 103 582-587, 2003. 

Hertzler SR, Savaiano DA Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance. Am J Clin Nutr 64 232-236,1996. 

Malabsorption of monosaccharides can also cause intestinal symptoms more commonly attributed to maldigestion of disaccharides. Glucose-galactose malabsorption is also inherited as an autosomal recessive trait. Symptoms occur in the affected neonate as soon as milk (lactose) is taken, but also follow ingestion of glucose- or galactose-containing... 

In patients whose maldigestion is difficult to control, other underlying conditions should be considered, such as noncompliance, infections of the gastrointestinal tract, celiac disease, lactose deficiency, inflammatory bowel disease, anatomical abnormalities, diabetes, and liver cirrhosis. This question is complicated by the abundance of small intestinal viscous glycoproteins in cystic fibrosis, prolonged intestinal transit times, which may provoke bacterial overgrowth [104], and absorption of the enzymes in their macromolecular form [105]. 

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