Luteolin 7- O- glucoside

Trihydroxyflavone-7-0-glucoside Luteolin-7-O-glucoside Seed exudate Medicago saliva S. meliloli... 

Compounds 1 = 4-hydroxycoumarin 2 = umbelliferon 3 = 4-methyl-esculetin 4 = isopimpinellin 5 = esculin 6 = flavone 7 = a-naphtoflavone 8 = kaempferol 9 = quercetin 10 = isoquercitrin 11 = robinetin 12 = robinin 13 = myricetin 14 = luteolin 7-O-glucoside 15 = rutin 16 = hes-peretin 17 = hespiridin 18 = naringin 19 = pelargonin chloride 20 = polargonin chloride 21 = malvin chloride. 

Examples of other antiviral fiavonoids isolated from medicinal plants also included luteolin-7-O-glucoside isolated from Youngia japonica (L.) DC. (Asteraceae), ° and three new fiavones named 5-carboxymethyl-4, 7-dihydroxyfiavone, its ethyl ester and butyl ester isolated from Selaginella moellendorjfii Hieron (Selaginellaceae), which displayed inhibitory activity in vitro on hepatitis B virus (HBV). ... 

Luteolin-4 - 3 D-glucoside Lf Luteolin-4 -0 3 D-glucoside LP ° Luteolin-7 O glucoside ... 

Substantial quantities of luteolin-7-O-glucuronide, luteolin-7-O-glucoside, and luteolin-7-O-rutinoside occur in Red Oak Leaf and Lollo Rosso, two red-leaved varieties of lettuce (Lactuca sativa) [Llorach et al., 2008], Polymethoxylated flavones such as nobiletin, scutellarein, sinensetin, and tangeretin (Fig. 1.8) are found exclusively in citrus species [Crozier et al., 2006c], while diosmetin-7-O-glucuronide has been isolated from the fruits of a Chinese herb, Luffa cylindrical. 

Fig. 5A,B Arnicae flos (1,4). Arnica montana (1) and Arnica chamissonis (4) show a similar TLC pattern of three orange-yellow flavonoid zones between the blue zones of chlorogenic acid (Rf — 0.45/Tl) and isochlorogenic acids (Rf 0.7-0.95/Tl), The upper zone is due to isoquercitrin and luteolin-7-O-glucoside (T4). The flavonoid glycoside zone in the R, range of hy peroside (3T/T2) is more highly concentrated in sample (4).

Equisetum arvense (1,2) the same flavonoid glycoside pattern as shown in Fig. 17A, but with a better separation in the Rj range of isoquercitrin, indicating the presence of an additional flavonoid glycoside (luteolin-7-O-glucoside ). 

Flavonoids are also present. De Laurentis et al. [34] isolated and identified a series of flavonoid compounds from the dried leaves of blooming cultivars of O. europaea hesperidin, rutin, luteolin-7-O-glucoside, apigenin, apigenin-7-O-glucoside, quercetin, kaempferol... 

The reports indicate the presence of terpenes, a-pinene, camphene, citral and beta-caryophyllene in the essential oil from the leaves and flavonoids such as casticin, orientin, isoorientin, luteolin, luteolin-7-O-glucoside, corymbosin, gardenins A and B, 3-O-desmethylartemetin, 5-0-desmethylnobiletin, 3, 4, 5,5, 6,7,8-heptamethoxyflavone, 3, 5-dihydroxy-4, 7,8-trimethoxyflavanone and 3, 5-dihydroxy-4, 6,7-trimethoxy... 

FIGURE 2.6 H/D exchange of five deprotonated flavonoid monosaccharides (a) Luteolin-4 -0-glucoside, (h) Luteolin-7-O-glucoside, (c) Orientin, (d) Astragalin, and (e) Quercitrin after 10 s reaction with D2O. (Reproduced from Zhang, J. Brodbelt, J.S. J. Am. Chem. Soc. 2004,126, 5906-5919. With permission from American Chemical Society.)... 

Hsu FL, Chen YC, Cheng JT (2000) Caffeic add as active principle from the fruit of Xanthium strumarium to lower plasma glucose in diabetic rats. Planta Med 66(3) 228-230 Hu C, Kitts DD (2004) Luteohn and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells. Mol CeU Biochem 265(1-2) 107-113... 

Artichoke (Cynara scolymus) is an ancient herbaceous pereimial plant originating from Mediterranean North Africa. The artichoke head, an immature flower constitutes the edible part of this vegetable which is grown widely around the world with Italy and Spain being the leading producers. Artichoke heads contain antioxidants and the main phenolic compounds are 5-0-caffeoylquinic acid with smaller amounts of 1-O-calFeoylquinic acid, 1,4-0-dicafFeoylquinic acid, luteolin-7-O-glucoside, luteohn-7-O-rutinoside... 

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