Lupin allergenicity

Alvarez-Alvarez J, Guillamon E, Crespo JF, Cuadrado C, Burbano C, Rodriguez J, Fernandez C, Muzquiz M (2005). Effects of extrusion, boiling, autoclaving, and microwave heating on lupine allergenicity. J. Agric. Food Chem., 53 1294-1298. 

Foss N, Duranti M, Magni C, Frokiaer H (2006). Assessment of lupin allergenicity in the cholera toxin model induction of IgE response depends on the intrinsic properties of the conglutins and matrix effects. Int. Arch. Allergy. Immunol, 141 141-150. 

Rojas-Hijazo B, Garces MM, Caballero ML, Alloza P, Moneo 1 (2006). Unsuspected lupin allergens hidden in food. Int. Arch. Allergy Immunol, 141 47-50. 

The most frequent elicitators of food allergy in children are peanuts and tree nuts [ 17]. In France the prevalence of food allergy has been estimated to be 3.2% [18]. Furthermore, in this study, food was identified as the most common cause of anaphylaxis. Here the major identified food allergens besides peanuts and tree nuts were shellfish, wheat and lupine flour [18]. 

Cereal flour, buckwheat flour, soy flour, seafood allergens, pork, sesame seeds, sunflower seeds, lupin, spinach, sarsaparilla root dust, cocoa, coffee dusts, green tea, egg protein, lactalbumin, milk powder, casein, honey, a-amylase, glucoamylase, pectinase, gluconase, pepsin, pectin, spices, carmine, flavorings... 

Lifrani, A., Dubarry, M., Rautureau, M., Aattouri, N., Boyaka, P.N., and Tome, D. 2005. Peanut-lupine antibody cross-reactivity is not associated to cross-allergenicity in peanut-sensitized mouse strains. Int Immunopharmacol 5 1427-1435. 

This list was amended in December 2006 with the addition of mollusks and lupin, as Directive 2006/142/EC, to account for the opinion delivered by the European Food Safety Authority (EFSA) referring to the allergenicity of these foods and the prevalence of such food allergy in European member states. 

Appendix Ilia of Directive 2003/89/EC (EC, 2004), to the list of major allergens that by mandate have to be labeled on prepackaged foods (EC, 2006) in accordance with an opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies (NDA, 2005). The legislative bodies in other countries, however, have not yet issued labeling regulations for lupin. For further details, see eur-Iex.europa.eu/LexUriServ/ LexUriServ.do uri=OJ L 2006 368 0110 0111EN PDF. 

De las Marinas D, CojocariuZ, EscuderoR, Pardo N, Sanz ML (2007). Anaphylaxis induced by lupine as a hidden allergen. J. Investig. Allergol Clin. Immunol, 17 283-284. 

Dooper MMBW, Plassen C, Holden L, Lindvik H, F ste CK (2009). IgE cross-reactivity between lupin conglutins and peanut allergens in serum of lupin-allergic individuals. J. Investig. Allergol. Clin. Immunol, 19 283-291. 

Guillamon E, Burbano C, Cuadrado C, et al. (2008). Effect of an instantaneous controlled pressure drop on in vitro allergenicity to lupins (Lupinus albus var. Multolupa). Int. Arch. Allergy Immunol, 145 9-14. 

Leduc V, Moneret-Vautrin DA, Guerin L (2002). Allergenicity of lupin flour. Allergie Immunol, 34 213-217. 

Lpvik M (2003). [Lupine-a sneaking food allergen ] Tidsskr. Nor. Luegeforen., 123 2076-2077. 

Smith WB, GiUis D, Kette FE (2004). Lupin a new hidden food allergen. Med J Aust., 181 219-220. 

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