Lung tumors prostate specific antigen

The use of classical serum tumor markers, e.g., for screening of breast, lung, or bowel cancer, has largely failed. Unanswered questions still remain about the pros and cons of prostate-specific antigen measurements. 

Figure 6.8 In vivo fluorescence imaging of human prostate cancer xenograft tumors. Mice were injected intravenously with GPI-functionalized QDs and observed for 4 h. (a) The prostate-specific membrane antigen (PSMA)-positive LNCaP tumor and PSMA-negative PC-3 tumor are indicated. Shown are representative images for animals in the prone position, (b) In situ (top row) and resected (bottom row) organs from a imaged at 4 h post-injection with color video and NIR fluorescence. (Ki, kidneys Du, duodenum Sp, spleen In, intestines Lu, lungs Li, liver Pa, pancreas Ab, abdominal wall Bl, bladder.) Reproduced by permission from Macmillan Publishers Ltd. Nat. Nanotechnol. Copyright (2009).

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