Lung cancer resveratrol

Recently, 3,4,5-trimethoxy-4 -bromo-cis-stilbene, considered a resveratrol analogue, has been reported to induce G2/M cell cycle arrest and apoptosis in human lung cancer cells [20]. 

Kubota T, Uemura Y, Kobayashi M, Taguchi H (2003) Combined effects of resveratrol and paclitaxel on lung cancer cells. Anticancer Res 23 4039-4046... 

Hecht SS, Kenney PM, Wang M, Trushin N, Agarwal S, Rao AV, Upadhyaya P. 1999. Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4-(methylnitrosamino)-l-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice. Cancer Lett 137 123-130. 

Additionally, several reports indicate that -resveratrol inhibits the proliferation of a wide variety of human cancer cells including breast, prostate, colon, gastric, lung, pancreatic, liver, thyroid, and ovarian cancers, leukemia, lymphoma, osteosarcoma, squamous cell carcinoma, multiple myeloma, and medulloblastoma [135]. Among the other stilbenoids, piceatannol, a- and s-viniferin, hopeaphenol, pallidol, ampelopsin A, vaticanol B and C, and pterostilbene also showed cytotoxicity and/or antiproliferative effect on different tumor cell lines [136-145]. 

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