Listeria vaccine

Conlan JW, et al. Immunization of mice with lipopeptide antigens encapsulated in novel liposomes prepared from the polar lipids of various Archaeobacteria elicits rapid and prolonged specific protective immunity against infection with the facultative intracellular pathogen. Listeria monocytogenes. Vaccine 2001 19 3509. 

Sirard, J.C., Fayolle, C., de Chastellier, C., Mock, M., Leclerc, C., Berche, P. (1997a). Intrac doplasmic delivery of listeriolysin O by a vaccinal strain of Bacillus anthracis induces CD8-mediated protection against Listeria monocytogenes. J. Immunol. 159 4435 3. 

Simon B E, Cornell K A, Clark T R, et al. (2003). DNA vaccination protects mice against challenge with Listeria monocytogenes expressing the hepatitis C virus NS3 protein. Infect. Immun. 71 6372-6380. 

Starks H, Bruhn KW, Shen H, Barry RA, Dubensky TW, Brockstedt D, Hinrichs DJ, Higgins DE, Miller JF, Giedlin M, Bouwer HG. Listeria monoc3dogenes as a vaccine vector virulence attenuation or existing antivector immunity does not diminish therapeutic efficacy. J Immunol 2004 173 420-427. 

Sewell DA, Douven D, Pan ZK et al. Regression of HPV-positive tumors treated with a new listeria monocytogenes vaccine. Arch Otolaryngol Head Neck Surg 2004 130(l) 92-97. 

The incidence of food-bome infections from Listeria monocytogenes has increased dramatically in the past years the lack of an effective vaccine against this intracellular pathogen has encouraged the use of archaeosomes entrapped Sags formulation. The vaccine not only enhances cytotoxic T cell response but also helps in the clearance of pathogens, thereby increasing the survival of immunized animals. ... 

Among kidney transplant recipients, the 5%-10% who experienced immunological complications (acute then chronic graft rejection) and, as a consequence, were exposed to intense immunosuppressive therapy during the first year become more susceptible to developing opportunistic infections (Pneumocystis proved, Listeria monocytogenes, Nocardia asteroides. Cryptococcus neoformans or Aspergillus). Tberefore, it is extremely important to take preventive measures, i.e., vaccinations and prophylaxis. 

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