Liquid chromatography detection

Mitchell TW, Savage JC, Gould DH. 1993. High-performance liquid-chromatography detection of sulfide in tissues from sulfide-treated mice. J Appl Toxicol 13 389-394. 

Gas-liquid chromatography detects thienothiophenes in crude Qj]204,2oj gjjjj coffee extract. ... 

Vidrine, D. W. Liquid Chromatography detection using FT-IR in Fourier Transform Infrared Spectroscopy (ed.) Ferraro, J. R., Basile, L. J., Vol. 2, p. 129, New York— San Francisco—London, Academic Press 1979... 

Determination of mandelic acid in urine has been recommended as a biomaiker of exposure to ethylbenzene. Several methods can be used to determine mandelic acid in urine samples. These include derivatization of the acid and GC analysis (detection limit, 1.0 mg/L) isotachophoresis (detection limit, 0.04 mmol/L) and high-performance liquid chromatography (detection limit, 0.01 mmol/L) (WHO, 1996a). 

Imazupyr Methanol None High-performance liquid chromatography, detection at 250 nm [73]... 

Matthees, D.P. and Purdy, W.C., Naphthyldiazomethane as a derivatizing agent for the high-performance liquid chromatography detection of bile acids, Anal. Chim. Acta, 109, 161, 1979. 

P. E. Nelson, S. L. Nolan, and K. R. Bedford, High-performance liquid chromatography detection of morphine by fluorescence after post-column derivatization, J. Chromatogr., 234 407 (1982). 

McLean, J.D. (1982). Carbon electrodes for liquid chromatography detection. Anal. Chem., 54, 1169-74. 

H. Gunasingham, B. T. Tay, and K. P. Ang, Automated Mercury Film Electrode for Flow Injection Analysis and High-Performance Liquid Chromatography Detection. Anal. Chem., 58 (1986) 1578. 

Jeurissen, S.M., F.W. Claassen, J. Havlik, et al. 2007. Development of an on-line high performance liquid chromatography detection system for human cytochrome P450 1A2 inhibitors in extracts of natural products. /. Chromatogr. A 1141(l) 81-89. 

In normal phase liquid chromatography, systems of this kind have been utilized to separate and monitor alkylammonium ions and dipeptides on columns containing naphthalenesulfonate in the stationary phase [3]. For carboxylic and sulfonic acids, dimethylprotriptyline has been used as the counter-ion [16]. Acetylcholine was isolated and measured as the picrate ion-pair in an extract from rat sciatic nerve [17], In reversed phase liquid chromatography, detection by the ion-pair technique has been performed via the presence of detectable ionic probe in the aqueous mobile phase. More recently this indirect detection method has developed very rapidly for organic ionized compounds, such as carboxylic acids, amines and amino acids [18, 19], and for inorganic anions [20, 21]. 

It is useful for the cell holder position to be adjustable so that the crucial portion of the sample that is illuminated by the light source and observed by the detector is offset from the center of the cuvette this helps to minimize inner filter effects. Some commercial instruments provide this facility. A great range of flow cells for use in flow analysis and high-performance liquid chromatography detection is available these generally have very short optical pathlengths, so inner filter effects are much less likely. 

Vidrine DW (1979) Liquid chromatography detection using FT-IR. In Ferraro JR and Basile LJ (eds.) Fourier Transform Infrared Spectroscopy Applications to Chemical Systems, pp. 129-164. New York Academic Press. 

The simultaneous sampling of all spectral channels by means of diode array spectrometry leads to realtime spectral data acquisition (usually 0.1s for the whole spectrum). Data processing and storage may add a supplementary 0.5 s delay. Consequently, diode array spectrometry is a first choice for dynamic system measurements (e.g., flow injection analysis and liquid chromatography detection, process control, fast kinetic measurements). Spectral averaging capabilities represent a corollary of the increased acquisition speed. 

Liquid chromatography Detects large molecules in complex mixtures alternative to process-GC and -MS Slow relatively complicated sample handling... 

D. Warren Vidrine, Liquid Chromatography Detection Using FTIR, in Fourier Transform Infrared Spectroscopy Applications to Chemical Systems, Volume 2, J. Ferraro and L. Basile, Eds., Academic Press, New York, 1979. 

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