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Lipitor - Atorvastatin calcium

Lipitor (atorvastatin calcium) is a synthetic lipid-lowering drug. The chemical name for Lipitor is [R-(R, R )]-2-(4-fluorophenyl)-j3, 5-dihydroxy-5-(l-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-lH-pyrrole-l-heptanoic acid, calcium salt (2 1) trihydrate. The molecular weight is 1209.42. It is a white... [Pg.84]

Lipitor (Atorvastatin calcium). Pfizer Inc. US Prescribing information, March 2007. [Pg.452]

Lipitor (atorvastatin calcium) (colesterol lowering, a blockbuster)... [Pg.472]

Analysis The active ingredient in Lipitor is atorvastatin calcium. Pfizer lost because of a deficiency in the way dependent Claim 6 related to Claims 1 and 2. The following chart is presented to help understand how this happened ... [Pg.454]

Lipitor is currently one of the best selling drugs for lowering cholesterol. Searching in WDI for Lipitor produces the page shown in Figure 10.1 [46]. The preferred name is Atorvastatin Calcium . WDI has information about the pharmacology, indications, interactions, and so on, hyperlinked for keyword search. [Pg.256]

USAN atorvastatin calcium Trade Name Lipitor Company Pfizer Approval 1996 M.W 1155.37... [Pg.113]

Atorvastatin calcium CI-981 DRG-0321 Lipitor PD 134298-38A. Hydroxymethylglutarate co-enzyme A reductase inhibitor. Hypolipidemic agent. Crystals a]o = -7.4° (DMSO c = 1). Parke-Da iis. [Pg.47]

Statins include atorvastatin calcium (Lipitor), cerivastatin (Baycol), fluvas-tatin (Lescol), lovastatin (Mevacor), pravastatin sodium (Pravachol), and simvastatin (Zocor). [Pg.392]

An interesting account of this is provided in Chapter 9, Atorvastatin Calcium (Lipitor) in Contemporary Drug Synthesis, Li, J.-J, Johnson, D.J., Sliskovic, D.R., Roth, B.D., Eds. (Wiley Interscience, Floboken, NJ,... [Pg.212]

The first statins were launched by Merck with lovastatin (Mevacor ) in 1987 and then simvistatin (Zocor ) in 1991. Bristol-Myers launched pravastatin (Pravacol ) in 1991 Pfizer commercialized atorvastatin calcium (Lipitor ) in 1997. As measured by annual sales, Lipitor is the most successful drug in the history of the pharmaceutical industry [13]. Rosuvastatin calcium (Crestor ) is AstraZeneca s top drug with 6.6 billion in annual sales [14]. [Pg.185]

See other pages where Lipitor - Atorvastatin calcium is mentioned: [Pg.167]    [Pg.336]    [Pg.353]    [Pg.333]    [Pg.6]    [Pg.632]    [Pg.333]    [Pg.167]    [Pg.336]    [Pg.353]    [Pg.333]    [Pg.6]    [Pg.632]    [Pg.333]    [Pg.113]    [Pg.113]    [Pg.114]    [Pg.115]    [Pg.115]    [Pg.117]    [Pg.119]    [Pg.121]    [Pg.123]    [Pg.229]    [Pg.113]    [Pg.113]    [Pg.114]    [Pg.115]    [Pg.115]    [Pg.117]    [Pg.119]    [Pg.121]    [Pg.123]    [Pg.229]    [Pg.312]    [Pg.528]    [Pg.757]    [Pg.92]    [Pg.37]   


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