Lipid chemistry and biochemistry

Since the knowledge of today is the key for the solutions of tomorrow, we are fortimate that the chapters on lipidoses are supplemented by a comprehensive account of lipid chemistry and biochemistry which has been coordinated by W. Stoffel. 

As mentioned previously, the chemistry and biochemistry of compartmentation in cubic phases is not as actively studied as that of hposomes and micelles however, these cubic phases have potential that should be explored further, mostly due to the large capacity to incorporate biomaterials, and the peculiarity of the restricted geometrical environment. For example the polycondensation of amino acids or other monomers inside the lipid, chiral channels might be explored, or other reactions where it would be advantageous to have relatively high concentrations of reagents in a restricted tubular environment. 

The book assumes a knowledge of chemistry and biochemistry but not of dairy chemistry. As the title suggests, the book has a stronger biochemical orientation than either Principles of Dairy Chemistry or Dairy Chemistry and Physics. In addition to a fairly in-depth treatment of the chemistry of the principal constituents of milk, i.e. water, lactose, lipids, proteins (including enzymes), salts and vitamins, various more applied aspects are also covered, e.g. heat-induced changes, cheese, protein-rich products and the applications of enzymes in dairy technology. The principal physical properties are also described. 

Blomquist G. J., Tillman-Wall J. A., Guo L., Quilici D., Gu P. and Schal C. (1993) Hydrocarbon and hydrocarbon derived sex pheromones in insects biochemistry and endocrine regulation. In Insect Lipids Chemistry and Biology, eds D. W. Stanley-Samuelson and D. R. Nelson, pp. 317-351. University of Nebraska Press, Lincoln. 

Kaya K. Chemistry and biochemistry of taurolipids. Prog. Lipid Res. 1992 31 87-108. 

Deuel, H.J. The Lipids, Their Chemistry and Biochemistry Interscience Publishers Inc. New York, London, 1955 Vol. II, p. 919. 

The symposium from which this book was developed was designed to review and present current research on the biosynthesis and metabolism of lipids in plants together with the chemistry and biochemistry of lipid interactions however, some presentations reported input from disciplines other than chemistry. This 22-chapter volume presents a loose classification of the papers presented at the symposium into four sections (1) Introduction, (2) Plant Lipid Metabolism and Plant-Plant Interactions, (3) Plant-Insect and Plant-Nematode Interactions, and (4) Plant-Microbial Interactions. 

The chemistry and biochemistry of the tocopherylquinones and tocopherols has been recently reviewed in some detail. The first recognized function of vitamin E was as an antisterility factor for the laboratory rat. However, it is now known to have multiple functions in vivo. For example, it is required for the maintenance of structural and functional integrity of skeletal, cardiac, and smooth muscle and, in some animals, the peripheral vascular system. Tocopherols also function as intracellular antioxidants, particularly with respect to the stabilization of ingested fats and perhaps products arising in the metabolic synthesis and degradation of lipids. It has also been proposed that the tocopherylquinones may have some functional role in electron transport systems. 

Lough, A.K. (1973) Prog. Chem. Fats Other Lipids 14, 1 8. The chemistry and biochemistry of phytanic, pristanic and related acids. 

Salmond CV, KroU RG, Booth IR (1984) The effect of food preservatives on pH homeostasis in Escherichia coli. J Gen Microbiol 130 2845-2850 Sambanthamurthi R, Sundram K, A. TY (2000a) Chemistry and biochemistry of palm oil. Prog Lipid Res 39 507-558... 

This book examines the chemistry and biochemistry of lipid oxidation from a solid redox biology platform highlights include the effects of lipid oxidation on diverse cell signaling pathways and inflammatory responses. The role of oxidized lipids in pathology includes chapters on cardiovascular disease, carcinogenesis, and age-related neurodegenerative disorders. 

This bode covers both established information and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease. It is COTiposed of three sections Section I Chemistry and Biochemistry of Lipid Oxidation Section II Sites of Biological Actions of Oxidized Lipids and Section IB Oxidized Lipids in Pathology and Disease. Within each section, chapters by specialists in the field explain the basic principles and address current ideas and recent findings on a selection of critical topics. 

Hitchcock, C. (1975) in Recent Advances in the Chemistry and Biochemistry of Plant Lipids (eds T. Galliard and E.L Mercer) Academic Press, New York, p. 1. 

Blomquist, G.J., and L.L. Jackson Chemistry and Biochemistry of Insect Waxes. Prog. Lipid Rese. 17, 319-345 (1979). 

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