Solutions, line cleaning

Innovation in line-cleaning solutions is a fertile area in which, on a regular basis, another formulation comes along which is claimed to deliver better cleaning capability. However any independent evidence to support such claims is typically non-existent. Furthermore it is surprising how tunes are played with the composition of line-cleaning solutions, especially with regard to claims for the concentration of components. Bizarre... 

A CIP system includes pipelines, interconnected with valves to direct fluid to appropriate locations, and the control circuit, which consists of interlines to control the valves that direct the cleaning solutions and water through the lines, and air lines which control and move the valves. A programmer controls the timing and the air flow to the valves on a set schedule. The 3A Standards for CIP components, equipment, and installation have been developed. A simple CIP system circuit is shown in Figure 11. 

FIGURE 9.15 Design of a SI separation system for on-line separation of actinides for ICP-MS detection, where the SI system handles clean solutions and reagents outside the radioactivity containment glove box, while the injection valve and separation column downstream handle radioactive solutions. 

The advantages and disadvantages of in-line microfiltration and cross-flow filtration are compared in Table 7.2. In general, in-line filtration is preferred as a polishing operation for already clean solutions, for example, to sterilize water... 

On-line cleaning may be achieved by the injection of chemical solutions into the process stream. A major difficulty arises from product contamination which may persist even after the dosing has been stopped. It is essentially an adaption of offline cleaning discussed in the next section. 

Micronox MX2628/ Kyzen Environmentally friendly, versatile aqueous solution with long tank life Removes latest lead-free technology from advanced packaging in batch or in-line cleaning machines 170 N/A N/A 93 0.05... 

Fig. 15 Mass changes of Zn films at open-circuit potential exposed to new (full line) and used (dash-dot line) alkaline cleaning solution. Electrodes Zn film on Au (with Cu overlayer) supported on 10-MHz AT-cut quartz crystal. Solution RIDOLINE industrial alkaline cleaner, pH 12.43. Temperature 316 K. (Reproduced from Ref [92] with permission from the Royal Society of Chemistry.)...

Building on this, other variables that get in the way of effective line cleaning include cheap, cheerful, and nonoptimised cleaning solutions (with compromises on strength, surfactants to reduce surface tension, sequesterants, and chelators to bind calcium, etc.), water (cold or hand hot, hard versus soft), and, most importantly, whether the process is essentially sialic or involves movement as mechanical action. 

Remedial action is straightforward and as recommended by the Brewers Association (2011) draught beer quaUty manual such that every 14days all FOB-stop devices should be cleaned in line, and cleaning solution vented out of the top and every three months all FOB-stop devices should be completely disassanbled and hand-cleaned . 

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