Le Blanc

Le Blanc C, Grillon G, Chambaret J P, Migus A and Antonetti A 1993 Compact and efficient multipass Ti sapphire system for femtosecond chirped-pulse amplification at the terawatt level Opt. Lett. 18 140-... 

It should be mentioned that soap only became a mass product following development of the soda industry (Le Blanc process). There was never a shortage of fats and fatty oils, only suitable alkalies. 

The author would like to thank Mr. J.M. Beurtier and Mrs. 1. Le Blanc (CF Comma, Rennes, France) and Dr. G. Nijman (Vredestein AB, Enschede, the Netherlands), and their coworkers for kindly submitting the samples that were used in generating the results discussed in this chapter. 

Nestle Research Centre Vers-Chez-Les-Blanc PO Box 44... 

Bolton, J. L. Le Blanc, J. C. Y. Siu, K. W. M. Reaction of quinone methides with proteins analysis of myoglobin adduct formation by electrospray mass spectrometry. Biol. Mass... 

Britain—the French National Academy of Sciences concluded that scarcely anyone has done so much for industry and received so little reward as did Le Blanc. ... 

J. B. Dumas. Deux Pieces Historiques Concernant Les Opinions de Lavoisier au Sujet de la Formation des Etres Organises et Celles de N. Le Blanc au Sujet de la Theorie des Engrais. Paris Hachette et Cie., 1860. Source for Leblanc s manure studies. 

Synthesis of biologically active epoxides were reported by Le Blanc et al. and were synthesized initially as a route into the pyrazole compounds shown in Sect. 3.2.1a Scheme 48 [80]. Scheme 35 shows the synthesis of two of the most active epoxides 139a and 139b. They were formed from the reaction of chal-cones (140a and 140b, respectively) by reaction with H2O2 and K2CO3 in MeOH... 

Pyrazoles were synthesized in the authors laboratory by Le Blanc et al. from the epoxy-ketone as already stated in Sect. 3.1.1a, Scheme 35 [80]. The synthetic strategy employed by Le Blanc et al. [80] was based upon that the strategy published by Bhat et al. [81] who also described the synthesis of pyrazoles but did not report cytotoxic evaluation on the synthesized compounds. Scheme 48 shows the synthesis of the most active compound (178). Dissolution of the epoxide (179) with a xylenes followed by treatment with p-toluenesulfonic acid and hydrazine hydrate produced the pure nitro-pyrazole 180 in good yield (60%). Catalytic hydrogenation with palladium on activated carbon allowed the amino-pyrazole (178) to be obtained in a pure form. This synthesis allowed relatively large numbers of compounds to be produced as the crude product was sufficiently pure. Yield, reaction time, and purification compared to reported approaches were improved [50, 61, and 81]. Cytotoxicity of these pyrazole analogs was disappointing. The planarity of these compounds may account for this, as CA-4, 7 is a twisted molecule. 

Leblanc (Also written LeBlanc and Le Blanc). An obsolete, two-stage process for making sodium carbonate from sodium chloride. In the first stage, the salt cake process, salt was heated with sulfuric acid, yielding sodium sulfate (salt cake) and gaseous hydrogen chloride ... 

Davis le blanc Initiatives to Modify TSCA Regulations... 

Li H, Michael Siu KW, Guevremont R, Le Blanc JCY (1997) Complexes of silver with peptides and proteins as produced in electrospray mass spectrometry. J Am Soc Mass Spectrom 8 781-792... 

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