Lactobacillus bifidus

Bernhardt The Isolation of a Crystalline Growth Factor for a Strain of Lactobacillus Bifidus. Arch. Biochem. Biophysics 48, 225 (1954). 

Acetyl-a- and -/9-D-Glucosaminides and their Mikrobiological Activity for Lactobacillus bifidus var. Penn. Arch. Biochem. Biophysics 54, 392 (1955). 277- —, P. N. Smith, C. S. Rose and P. Gyorgy Enzymatic Synthesis of a Growth Factor for Lactobacillus Bifidus Var. Penn. J. biol. Chemistry 208, 299 (1954). 

Gyorgy, P., Jeanloz, R. W., von Nicolai, H., and Zilliken, F. (1974). Undialyzable growth factors for Lactobacillus bifidus var. pennsylvanicus. Protective effect of sialic acid bound to glycoproteins and oligosaccharides against bacterial degradation. Eur. J. Biochem. 43,29-33. 

Calcium is necessary for cell division in Lactobacillus bifidus,445 and for the transition of L. bulgaricus446 from long filamentous chains to short bacilloid rods. 

An enzyme from Lactobacillus bifidus has been purified it catalyzes the following reaction. 

Table 4 Protective Effect of Na-Glutamate and High Molecular Weight Substances in Freeze-Drying of Lactobacillus bifidus Cells...

V. Damjanovic and D. Radulovic, Predicting the stability of freeze-dried Lactobacillus bifidus by the accelerated storage test. Cryobiology 5 101-104, 1968. 

Lactobacillus bifidus growth factor activity (see Section 9.6)... 

Tomarelli et al. (T31) reported that rats grow more rapidly whrai feeding is associated with administration of hog gastric mucin. This effect may be due to its content of Lactobacillus bifidus factor. Findings were similar in children. 

Springer, G. F., and Gyorgy, P., Blood group mucoids in growth promotion of Lactobacillus bifidus var. perm. Federation Proc. 12, 272-273 (1953). Abstr. 

A number of reviews have now appeared on the subject. It has been known since 1900 that differences exist between the intestinal flora of breast-fed babies and those fed on cows milk, the flora of the former being composed almost exclusively of L. bifidus. In 1926, it was shown that a growth factor for L. bifidus occurs, associated with the lactose fraction in whey, in human milk, but it was not found in cream, in the proteins, or in the inorganic material. Later the nutritional requirements of L. bifidus were reinvestigated and, in the course of this work, there was isolated, from the feces of infants, a variant of L. bifidus which gave only a scanty growth on the normal media, but which responded to the addition of human milk. This variant was named Lactobacillus bifidus var. pennsyl-... 

Exodextranases catalyze a stepwise hydrolysis of the dextran molecule to yield D-glucose and a residual dextran they have been extracted from cultures of species of Bacillus," Bacteroides, and Lactobacillus bifidus. These enzymes have not, however, been utilized in structural studies. Endodextranases have been isolated from exocellular fluids or cell extracts (or both) of the fungi PenidUium funiculosutn, P. lilacv-... 

Gyorgy P, Norris RF, Rose CS. A variant of Lactobacillus bifidus requiring a special growth factor. Arch Biochem Biophys 1954 48 193-201. 

C12H23NO10 341.314 Isol. from porcine gastric mucin, human milk, glycoproteins with human blood group A activity, goat colostrum and from fetuin. Growth factor for Lactobacillus bifidus. [a]g- +78.2 (3 min) +63.1 (3h) (c, 1.25 in H2O). 

LACTOBACILLUS BIFIDUS GROWTH PROMOTING FACTOR ( Gyorgy )... 

From a consideration of the predominance of Lactobacillus bifidus in the feces of breast-fed but not of artificially fed infants, a chromatographic study was made by Ross of the amino acids in the feces of breast-fed and artificially fed (dried milk) infants. In the breast-fed infant s feces,... 

A substance found in human breast milk which promotes the growth of Lactobacillus bifidus in the intestines of infants. L. bifidus protects infants against various types of bacterial infections in the digestive tract. 

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