Lactic acid isopropyl ester

Synonyms lsopropyl-S-(-)-2-hydroxy propionate Lactic acid, Isopropyl ester 1-Methylethyl 2-hydroxypropanoate Propanoic acid, 2-hydroxy-,... 

Lactic acid, isopropyl ester. See Isopropyl lactate... 

Lactic acid isopropyl ester. See Isopropyl lactate Isopropyl-S-lactate Lactic acid, magnesium salt. See Magnesium lactate... 

S) -(-)-Lactic acid butyl ester see Butyl (S)-(-)-2-hydroxy-2-methylpropanoate (S)-(-)-Lactic acid ethyl ester see Ethyl (S)-(-)-2-hydroxypropanoate (S)-(-)-Lactic acid isopropyl ester see Isopropyl (S)-(-)-2-hydroxy-2-methylpropanoate Lauryl alcohol Dodecan-l-ol... 

Several lactic acid derivatives were used by Gessner et al. for the determination of the enantiomeric purity of flavor substances such as chiral alcohols from natural sources. Diastereomeric 0-acetyl-, propionyl-, and hexanoyllactic acid esters of the chiral alcohols were separated by GLC (155). A report from the same laboratories described characterization of several chiral aroma substances that are S-lactones. The lactones were hydrolyzed to the corresponding hydroxy acids, and the acid moiety was esterified to the isopropyl ester. The remaining hydroxyl group was esterified with (R)-2-phenylpropionic add chloride or [30], and the diastereomeric derivatives were separated using preparative silica gel LC. The derivatives were also separated on an analytical scale by GLC (156). 

The enantiomers of methyl, ethyl, isopropyl esters of lactic acid can be directly separated using a "Pirkle" chiral stationary phase. 

Fig. 8 Direct separation of the enantiomers of methyl, ethyl and isopropyl esters of lactic acid by LC on CSP of Pirkle" type (racemic mixtures).

Definition Isopropyl ester of lactic acid Empirical CsHijOj Formula CH3CH(OH)COOCH(CH,)2 Properties M.w. 132.18 Toxicology LDLo (IM, guinea pig) 2500 mg/kg Uses Solvent for paints and coatings, electronics, printed circuit boards, metal industry... 

Propanoic acid butyl ester. See n-Bulyl propionate Propanoic acid, ethenyl ester. See Vinyl propionate Propanoic acid ethyl ester. See Ethyl propionate Propanoic acid, 2-hydrorqr-. See Lactic acid Propanoic acid, 2-hydrorqr-, ammonium salt SeeAmmonium lactate Propanoic acid, 2-hydrorqr-, butyl ester. See Butyl lactate Propanoic acid, 2-hydrorqr-, 1-methylethyl ester. See Isopropyl lactate Propanoic acid, 2-methyl-, monoester with 2,2,4-trimethyl-1,3-pentanediol. See2,2,4-Trimethyl-1,3-pentanediol isobutyrate Propanoic acid, pentyl ester. SeeAmyl propionate Propanoic acid, propyl ester. See Propyl propionate Propanoic acid, 3,3 -thiobis-, dioctadecyl ester. See Disteatyl thiodipro-pionate... 

Calcium sulfate dihydrate Citric acid Citric acid esters of mono- and diglycerides of fatty acids Diacetyl tartaric acid esters of mono-and diglycerides Dimagnesium diphosphate Disodium citrate Disodium EDTA Distearyl citrate Gluconolactone y-Heptalactone Isopropyl citrate Lactic acid esters of mono-, and diglycerides of fatty acids Monosodium tartrate Oxystearin Pentasodium triphosphate... 

Charles Friedel (1832-1899) Friedel was Professor of Chemistry at the Sorbonne. He did extensive work on ketones, lactic acid, and glycerol and he discovered isopropyl alcohol. He is best known for his studies of the use of aluminum chloride in the synthesis of aromatic products (Friedel-Crafts reaction, 1877). Friedel prepared a series of esters of silicic acid and demonstrated the analogy between the compounds of carbon and silicon, meanwhile confirming the atomic weight of silicon. He determined the... 

---