Junin fever

Disappearance of predators may also imbalance the equilibrium, and the problem scales up, such as the disappearance of foxes, predators of the deer mouse, which has allowed spreading of the hantavirus in the US, carried by mice (Levins 1993). Similarly, Sabia virus has emerged in Brazil, Guaranito virus in Venezuela (Lisieux 1994), machupo virus in Bolivia, and Junin fever in Argentine (Garrett 1994). In contrast, in a robust ecosystem, elimination of a predator provides space for another predator, such as in the disappearance of the coyote, which has opened the control of field mice to snakes and owls. When both predator and prey are endangered, it may occur that the prey develops resistance. This is taken into account in Volterra s equation (Ehrlich 1986). 

Hemorrhagic fever viruses (including Ebola, Marburg, Lassa, and the South American arenaviruses, such as Machupo, Junin, and Guanarito)... 

Barradas JS, Errea MI et al (2011) Imidazo[2,l-b]thiazole carbohydrate derivatives synthesis and antiviral activity against Junin virus, agent of argentine hemorrhagic fever. Eur J Med Chem 46 259-264... 

Arenaviruses (Lassa (Lassa fever), Junin (Argentine hemorrhagic fever), and related viruses)... 

Junin Hemorrhagic Fever hemorrhagic symptoms including nose bleed, Abraded Skin Reservoir Rodents... 

Argentine hemorrhagic fever (Junin) Tacaribe Virus complex Arenavirus Virus Probable... 

Hemorrhagic fever agents including, but not limited to, Crimean hermorrhagic fever (Congo), Junin, Machupo viruses, and Korean hemorrhagic fever viruses. 

Helminthosporium oryzae Hog Cholera Junin Hemorrhagic Fever Kyasanur Forest Lassa Fever... 

The Junin virus that causes Argentine hemorrhagic fever is carried by a field mouse, Calomys colosus, and is associated with agricultural activities in the pampas of Argentina, where 300 to 600 cases have occurred every year since 1955.2 In Bo-... 

A similar dose of ribavirin begun within 4 days of disease is efficacious in patients with HFRS.33 In Argentina, ribavirin has been shown to reduce viro-logical parameters of Junin virus infection (ie, Argentine hemorrhagic fever), and is now used routinely as an adjunct to immune plasma. However, ribavirin does not penetrate the brain and is expected to protect only against the visceral, not the neurological phase of Junin infection. 

Ribavirin is an antiviral drug with efficacy for treatment of the arenaviruses and bunyaviruses. Passively administered antibody is also effective in therapy of some viral hemorrhagic fevers. The only licensed vaccine available for VHF agents is for yellow fever. Experimental vaccines exist for Junin, RVF, hantaan, and dengue viruses, but these will not be licensed in the near future. 

Vaccines are available for yellow fever (YF), Rift Valley fever (RVF), and Argentine hemorrhagic fever (Junin virus, JUN). Cross protection against Bolivian hemorrhagic fever may also be provided by the Junin vaccine. These are the only vaccines available for any of this set of diseases and will be effective only if personnel are immunized before exposure. Only yellow fever vaccine is licensed by the FDA the others are used in the United States under END protocols and can only be obtained through the CDC. 

South American hemorrhagic fever viruses (Junin, Machupo, Sabia, Flexal, Guanarito)... 

Arenavirus (Lassa fever virus, lymphocytic choriomeningitis virus, Machupo virus, and Junin virus). Enveloped, helical, ambisense, and ssRNA (two segments). Synthesis occurs in the host cell cytoplasm maturation involves budding from the host cell plasma membrane. Virions contain ribosomes. The human pathogens Lassa, Machuppo, and Junin viruses are Biosafety Level 4 pathogens - they must be handled in the laboratory under maximum containment conditions. 

Arenavirus (Lassa fever virus, lymphocytic choriomeningitis virus, Machupo virus, Junin virus)... 

---